Non-invasive detection of human cardiomyocyte death using methylation patterns of circulating DNA

The detection of cardiomyocyte death is a critical aspect in the diagnosis and monitoring of heart diseases. Here the authors show that cardiomyocyte-specific methylation patterns of circulating cell-free DNA may serve as a biomarker of cardiac cell death in infarcted and septic patients.

Guardado en:

Detalles Bibliográficos
Autores principales:	Hai Zemmour, David Planer, Judith Magenheim, Joshua Moss, Daniel Neiman, Dan Gilon, Amit Korach, Benjamin Glaser, Ruth Shemer, Giora Landesberg, Yuval Dor
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3d19d38519134934b5a7135c3d3d3ad2
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:3d19d38519134934b5a7135c3d3d3ad2
record_format	dspace
spelling	oai:doaj.org-article:3d19d38519134934b5a7135c3d3d3ad22021-12-02T15:34:21ZNon-invasive detection of human cardiomyocyte death using methylation patterns of circulating DNA10.1038/s41467-018-03961-y2041-1723https://doaj.org/article/3d19d38519134934b5a7135c3d3d3ad22018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03961-yhttps://doaj.org/toc/2041-1723The detection of cardiomyocyte death is a critical aspect in the diagnosis and monitoring of heart diseases. Here the authors show that cardiomyocyte-specific methylation patterns of circulating cell-free DNA may serve as a biomarker of cardiac cell death in infarcted and septic patients.Hai ZemmourDavid PlanerJudith MagenheimJoshua MossDaniel NeimanDan GilonAmit KorachBenjamin GlaserRuth ShemerGiora LandesbergYuval DorNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hai Zemmour David Planer Judith Magenheim Joshua Moss Daniel Neiman Dan Gilon Amit Korach Benjamin Glaser Ruth Shemer Giora Landesberg Yuval Dor Non-invasive detection of human cardiomyocyte death using methylation patterns of circulating DNA
description	The detection of cardiomyocyte death is a critical aspect in the diagnosis and monitoring of heart diseases. Here the authors show that cardiomyocyte-specific methylation patterns of circulating cell-free DNA may serve as a biomarker of cardiac cell death in infarcted and septic patients.
format	article
author	Hai Zemmour David Planer Judith Magenheim Joshua Moss Daniel Neiman Dan Gilon Amit Korach Benjamin Glaser Ruth Shemer Giora Landesberg Yuval Dor
author_facet	Hai Zemmour David Planer Judith Magenheim Joshua Moss Daniel Neiman Dan Gilon Amit Korach Benjamin Glaser Ruth Shemer Giora Landesberg Yuval Dor
author_sort	Hai Zemmour
title	Non-invasive detection of human cardiomyocyte death using methylation patterns of circulating DNA
title_short	Non-invasive detection of human cardiomyocyte death using methylation patterns of circulating DNA
title_full	Non-invasive detection of human cardiomyocyte death using methylation patterns of circulating DNA
title_fullStr	Non-invasive detection of human cardiomyocyte death using methylation patterns of circulating DNA
title_full_unstemmed	Non-invasive detection of human cardiomyocyte death using methylation patterns of circulating DNA
title_sort	non-invasive detection of human cardiomyocyte death using methylation patterns of circulating dna
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/3d19d38519134934b5a7135c3d3d3ad2
work_keys_str_mv	AT haizemmour noninvasivedetectionofhumancardiomyocytedeathusingmethylationpatternsofcirculatingdna AT davidplaner noninvasivedetectionofhumancardiomyocytedeathusingmethylationpatternsofcirculatingdna AT judithmagenheim noninvasivedetectionofhumancardiomyocytedeathusingmethylationpatternsofcirculatingdna AT joshuamoss noninvasivedetectionofhumancardiomyocytedeathusingmethylationpatternsofcirculatingdna AT danielneiman noninvasivedetectionofhumancardiomyocytedeathusingmethylationpatternsofcirculatingdna AT dangilon noninvasivedetectionofhumancardiomyocytedeathusingmethylationpatternsofcirculatingdna AT amitkorach noninvasivedetectionofhumancardiomyocytedeathusingmethylationpatternsofcirculatingdna AT benjaminglaser noninvasivedetectionofhumancardiomyocytedeathusingmethylationpatternsofcirculatingdna AT ruthshemer noninvasivedetectionofhumancardiomyocytedeathusingmethylationpatternsofcirculatingdna AT gioralandesberg noninvasivedetectionofhumancardiomyocytedeathusingmethylationpatternsofcirculatingdna AT yuvaldor noninvasivedetectionofhumancardiomyocytedeathusingmethylationpatternsofcirculatingdna
_version_	1718386832953049088

Non-invasive detection of human cardiomyocyte death using methylation patterns of circulating DNA

Ejemplares similares