Non-invasive detection of human cardiomyocyte death using methylation patterns of circulating DNA
The detection of cardiomyocyte death is a critical aspect in the diagnosis and monitoring of heart diseases. Here the authors show that cardiomyocyte-specific methylation patterns of circulating cell-free DNA may serve as a biomarker of cardiac cell death in infarcted and septic patients.
Enregistré dans:
Auteurs principaux: | Hai Zemmour, David Planer, Judith Magenheim, Joshua Moss, Daniel Neiman, Dan Gilon, Amit Korach, Benjamin Glaser, Ruth Shemer, Giora Landesberg, Yuval Dor |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2018
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/3d19d38519134934b5a7135c3d3d3ad2 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Comprehensive human cell-type methylation atlas reveals origins of circulating cell-free DNA in health and disease
par: Joshua Moss, et autres
Publié: (2018) -
Regulation of cardiomyocyte DNA damage and cell death by the type 2A protein phosphatase regulatory protein alpha4
par: Jonathan Cowan, et autres
Publié: (2021) -
Subcellular Localization of Connexin 26 in Cardiomyocytes and in Cardiomyocyte-Derived Extracellular Vesicles
par: Alessandra Falleni, et autres
Publié: (2021) -
Circulating cell-free DNA-based methylation patterns for breast cancer diagnosis
par: Xianyu Zhang, et autres
Publié: (2021) -
Sparsely methylated mitochondrial cell free DNA released from cardiomyocytes contributes to systemic inflammatory response accompanied by atrial fibrillation
par: Masahiro Yamazoe, et autres
Publié: (2021)