Predictors of Atrial Fibrillation Recurrence after Catheter Ablation: Data from the German Ablation Registry

Abstract Catheter ablation (CA) for atrial fibrillation (AF) has emerged as a widespread first or second line treatment option. However, up to 45% of patients (pts) show recurrence of AF within 12 month after CA. We present prospective multicenter registry data comparing characteristics of pts with...

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Auteurs principaux:	A. Sultan, J. Lüker, D. Andresen, K. H. Kuck, E. Hoffmann, J. Brachmann, M. Hochadel, S. Willems, L. Eckardt, T. Lewalter, J. Senges, D. Steven
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2017
Sujets:	Medicine R Science Q
Accès en ligne:	https://doaj.org/article/3d1a033505964f509dca7fc739e413e2
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spelling	oai:doaj.org-article:3d1a033505964f509dca7fc739e413e22021-12-02T15:05:12ZPredictors of Atrial Fibrillation Recurrence after Catheter Ablation: Data from the German Ablation Registry10.1038/s41598-017-16938-62045-2322https://doaj.org/article/3d1a033505964f509dca7fc739e413e22017-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-16938-6https://doaj.org/toc/2045-2322Abstract Catheter ablation (CA) for atrial fibrillation (AF) has emerged as a widespread first or second line treatment option. However, up to 45% of patients (pts) show recurrence of AF within 12 month after CA. We present prospective multicenter registry data comparing characteristics of pts with and without recurrence of AF within the first year after CA. This study comprises all pts with complete follow-up one year after CA (1-y-FU; n = 3679). During 1y-FU in 1687 (45.9%) pts recurrence of AF occurred. The multivariate analysis revealed female sex and AF type prior to the procedure as predictors for AF recurrence. Furthermore, comorbidities such as valvular heart disease and renal failure as well as an early AF relapse were also predictors of AF recurrence during 1-y-FU. However, despite an AF recurrence rate of 45.9%, the majority of these pts (72.4%) reported a significant alleviation of clinical symptoms. In conclusion in pts with initially successful CA for AF female sex, AF type, in-hospital AF relapse and comorbidities such as renal failure and valvular heart disease are independent predictors for AF recurrence during 1-y-FU. However, the majority of pts deemed their interventions as successful with significant reduction of symptoms irrespective of AF.A. SultanJ. LükerD. AndresenK. H. KuckE. HoffmannJ. BrachmannM. HochadelS. WillemsL. EckardtT. LewalterJ. SengesD. StevenNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q A. Sultan J. Lüker D. Andresen K. H. Kuck E. Hoffmann J. Brachmann M. Hochadel S. Willems L. Eckardt T. Lewalter J. Senges D. Steven Predictors of Atrial Fibrillation Recurrence after Catheter Ablation: Data from the German Ablation Registry
description	Abstract Catheter ablation (CA) for atrial fibrillation (AF) has emerged as a widespread first or second line treatment option. However, up to 45% of patients (pts) show recurrence of AF within 12 month after CA. We present prospective multicenter registry data comparing characteristics of pts with and without recurrence of AF within the first year after CA. This study comprises all pts with complete follow-up one year after CA (1-y-FU; n = 3679). During 1y-FU in 1687 (45.9%) pts recurrence of AF occurred. The multivariate analysis revealed female sex and AF type prior to the procedure as predictors for AF recurrence. Furthermore, comorbidities such as valvular heart disease and renal failure as well as an early AF relapse were also predictors of AF recurrence during 1-y-FU. However, despite an AF recurrence rate of 45.9%, the majority of these pts (72.4%) reported a significant alleviation of clinical symptoms. In conclusion in pts with initially successful CA for AF female sex, AF type, in-hospital AF relapse and comorbidities such as renal failure and valvular heart disease are independent predictors for AF recurrence during 1-y-FU. However, the majority of pts deemed their interventions as successful with significant reduction of symptoms irrespective of AF.
format	article
author	A. Sultan J. Lüker D. Andresen K. H. Kuck E. Hoffmann J. Brachmann M. Hochadel S. Willems L. Eckardt T. Lewalter J. Senges D. Steven
author_facet	A. Sultan J. Lüker D. Andresen K. H. Kuck E. Hoffmann J. Brachmann M. Hochadel S. Willems L. Eckardt T. Lewalter J. Senges D. Steven
author_sort	A. Sultan
title	Predictors of Atrial Fibrillation Recurrence after Catheter Ablation: Data from the German Ablation Registry
title_short	Predictors of Atrial Fibrillation Recurrence after Catheter Ablation: Data from the German Ablation Registry
title_full	Predictors of Atrial Fibrillation Recurrence after Catheter Ablation: Data from the German Ablation Registry
title_fullStr	Predictors of Atrial Fibrillation Recurrence after Catheter Ablation: Data from the German Ablation Registry
title_full_unstemmed	Predictors of Atrial Fibrillation Recurrence after Catheter Ablation: Data from the German Ablation Registry
title_sort	predictors of atrial fibrillation recurrence after catheter ablation: data from the german ablation registry
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/3d1a033505964f509dca7fc739e413e2
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Predictors of Atrial Fibrillation Recurrence after Catheter Ablation: Data from the German Ablation Registry

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