The CD153 vaccine is a senotherapeutic option for preventing the accumulation of senescent T cells in mice
Senotherapy, the removal of aged T cells, is an effective approach to attenuate age-related diseases. Here the authors report a CD153 targeting vaccine that prevents the accumulation of senescent adipose tissue T cells in mice on high-fat diet, which is associated with improved glucose tolerance.
Guardado en:
Autores principales: | Shota Yoshida, Hironori Nakagami, Hiroki Hayashi, Yuka Ikeda, Jiao Sun, Akiko Tenma, Hideki Tomioka, Tomohiro Kawano, Munehisa Shimamura, Ryuichi Morishita, Hiromi Rakugi |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/3d1a44c22d254ecbacf92a2ba8dc772e |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Decrease in blood pressure and regression of cardiovascular complications by angiotensin II vaccine in mice.
por: Futoshi Nakagami, et al.
Publicado: (2013) -
Development of anti-thrombotic vaccine against human S100A9 in rhesus monkey
por: Munehisa Shimamura, et al.
Publicado: (2021) -
Biomolecular Evaluation of Piceatannol’s Effects in Counteracting the Senescence of Mesenchymal Stromal Cells: A New Candidate for Senotherapeutics?
por: Nicola Alessio, et al.
Publicado: (2021) -
Acta No. 153
por: Banco Central de Chile
Publicado: (2019) -
Hepatocyte Growth Factor Prevented High-Fat Diet-Induced Obesity and Improved Insulin Resistance in Mice
por: Jun Muratsu, et al.
Publicado: (2017)