Variations of Prevalence and Incidence of Atrial Fibrillation and Oral Anticoagulation Rate According to Different Analysis Approaches

Abstract The reported incidence and prevalence of atrial fibrillation (AF) has been inconsistent across published studies. Using the National Health Insurance Service database of Korea, the prevalence and incidence of AF, and oral anticoagulation (OAC) use of AF patients were explored according to t...

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Autores principales:	Pil-Sung Yang, Soorack Ryu, Daehoon Kim, Eunsun Jang, Hee Tae Yu, Tae-Hoon Kim, Jinseub Hwang, Boyoung Joung, Gregory Y. H. Lip
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/3d38473217134c36b90c9ed7eea526da
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spelling	oai:doaj.org-article:3d38473217134c36b90c9ed7eea526da2021-12-02T12:32:11ZVariations of Prevalence and Incidence of Atrial Fibrillation and Oral Anticoagulation Rate According to Different Analysis Approaches10.1038/s41598-018-25111-62045-2322https://doaj.org/article/3d38473217134c36b90c9ed7eea526da2018-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-018-25111-6https://doaj.org/toc/2045-2322Abstract The reported incidence and prevalence of atrial fibrillation (AF) has been inconsistent across published studies. Using the National Health Insurance Service database of Korea, the prevalence and incidence of AF, and oral anticoagulation (OAC) use of AF patients were explored according to three different approaches; ‘formal approach’, considering individual AF diagnosis and mortality; ‘limited diagnosis approach’, using upper 5 main diagnosis; and ‘medical use approach’, using the number of medical use AF population by year without considering individual AF history and mortality. The AF prevalence progressively increased by 2.46-fold from 0.50% in 2004 to 1.54% in 2015 when using a ‘formal approach’ (p for trend <0.001). The overall prevalence was 1.09% and 0.97% when using a ‘formal approach’ and ‘limited diagnosis approaches’, respectively. Overall prevalence decreased to 0.52% with a ‘medical use approach’. The trend of annual AF incidence was stable when using a ‘formal approach’, but increased by 15% when using a ‘medical use approach’. OAC rate in 2015 was 2.1 times higher when using a ‘medical use approach’ compared to using a ‘formal approach’ (40.3% vs. 19.1%, p < 0.001). Given the wide variability in prevalence and incidence figures with different analysis approaches, careful attention to the analysis methodology is needed.Pil-Sung YangSoorack RyuDaehoon KimEunsun JangHee Tae YuTae-Hoon KimJinseub HwangBoyoung JoungGregory Y. H. LipNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 8, Iss 1, Pp 1-5 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Pil-Sung Yang Soorack Ryu Daehoon Kim Eunsun Jang Hee Tae Yu Tae-Hoon Kim Jinseub Hwang Boyoung Joung Gregory Y. H. Lip Variations of Prevalence and Incidence of Atrial Fibrillation and Oral Anticoagulation Rate According to Different Analysis Approaches
description	Abstract The reported incidence and prevalence of atrial fibrillation (AF) has been inconsistent across published studies. Using the National Health Insurance Service database of Korea, the prevalence and incidence of AF, and oral anticoagulation (OAC) use of AF patients were explored according to three different approaches; ‘formal approach’, considering individual AF diagnosis and mortality; ‘limited diagnosis approach’, using upper 5 main diagnosis; and ‘medical use approach’, using the number of medical use AF population by year without considering individual AF history and mortality. The AF prevalence progressively increased by 2.46-fold from 0.50% in 2004 to 1.54% in 2015 when using a ‘formal approach’ (p for trend <0.001). The overall prevalence was 1.09% and 0.97% when using a ‘formal approach’ and ‘limited diagnosis approaches’, respectively. Overall prevalence decreased to 0.52% with a ‘medical use approach’. The trend of annual AF incidence was stable when using a ‘formal approach’, but increased by 15% when using a ‘medical use approach’. OAC rate in 2015 was 2.1 times higher when using a ‘medical use approach’ compared to using a ‘formal approach’ (40.3% vs. 19.1%, p < 0.001). Given the wide variability in prevalence and incidence figures with different analysis approaches, careful attention to the analysis methodology is needed.
format	article
author	Pil-Sung Yang Soorack Ryu Daehoon Kim Eunsun Jang Hee Tae Yu Tae-Hoon Kim Jinseub Hwang Boyoung Joung Gregory Y. H. Lip
author_facet	Pil-Sung Yang Soorack Ryu Daehoon Kim Eunsun Jang Hee Tae Yu Tae-Hoon Kim Jinseub Hwang Boyoung Joung Gregory Y. H. Lip
author_sort	Pil-Sung Yang
title	Variations of Prevalence and Incidence of Atrial Fibrillation and Oral Anticoagulation Rate According to Different Analysis Approaches
title_short	Variations of Prevalence and Incidence of Atrial Fibrillation and Oral Anticoagulation Rate According to Different Analysis Approaches
title_full	Variations of Prevalence and Incidence of Atrial Fibrillation and Oral Anticoagulation Rate According to Different Analysis Approaches
title_fullStr	Variations of Prevalence and Incidence of Atrial Fibrillation and Oral Anticoagulation Rate According to Different Analysis Approaches
title_full_unstemmed	Variations of Prevalence and Incidence of Atrial Fibrillation and Oral Anticoagulation Rate According to Different Analysis Approaches
title_sort	variations of prevalence and incidence of atrial fibrillation and oral anticoagulation rate according to different analysis approaches
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/3d38473217134c36b90c9ed7eea526da
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Variations of Prevalence and Incidence of Atrial Fibrillation and Oral Anticoagulation Rate According to Different Analysis Approaches

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