The effect of various intake levels of soybean oil on blood glucose and inflammation in mice

The effects of various intake levels of soybean oil on carbohydrate metabolism and inflammation in mice were studied. Mice were supplied with different diets, in which soybean oil provided 5, 10, 15, 20, 25, and 30% of total energy. Blood glucose indices, blood fat indices, inflammatory factors, and...

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Autores principales:	Xinli Pei, Zhongguo Xie, Jing Wang, Kaiwen Shi, Fei Han, Aike Li, Haiying Liu
Formato:	article
Lenguaje:	EN
Publicado:	Taylor & Francis Group 2018
Materias:	soybean oil intake fasting blood glucose inflammatory factors Agriculture (General) S1-972 Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/3d3848c6e819482a951998ac829b865c
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spelling	oai:doaj.org-article:3d3848c6e819482a951998ac829b865c2021-11-26T11:19:46ZThe effect of various intake levels of soybean oil on blood glucose and inflammation in mice0954-01051465-344310.1080/09540105.2017.1409194https://doaj.org/article/3d3848c6e819482a951998ac829b865c2018-01-01T00:00:00Zhttp://dx.doi.org/10.1080/09540105.2017.1409194https://doaj.org/toc/0954-0105https://doaj.org/toc/1465-3443The effects of various intake levels of soybean oil on carbohydrate metabolism and inflammation in mice were studied. Mice were supplied with different diets, in which soybean oil provided 5, 10, 15, 20, 25, and 30% of total energy. Blood glucose indices, blood fat indices, inflammatory factors, and gene expression of insulin receptor substrates 1 and 2 Insulin receptor substrate 1 (IRS1) and Insulin receptor substrate 2 (IRS2) were analyzed. The results showed that higher intake of soybean oil can lead to excessive weight gain, higher levels of fasting blood glucose and serum insulin, increased levels of tumor necrosis factor-α, interleukin 6, hyper-sensitive C-reactive protein, and reduced expression of IRS1 and IRS2 mRNA. Primarily, we found that reduced intake of soybean oil led to a similar trend to that of a high soybean oil diet. The optimal intake of soybean oil, as supplied in the diet, was about 15–20%.Xinli PeiZhongguo XieJing WangKaiwen ShiFei HanAike LiHaiying LiuTaylor & Francis Grouparticlesoybean oilintakefasting blood glucoseinflammatory factorsAgriculture (General)S1-972Immunologic diseases. AllergyRC581-607ENFood and Agricultural Immunology, Vol 29, Iss 1, Pp 511-523 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	soybean oil intake fasting blood glucose inflammatory factors Agriculture (General) S1-972 Immunologic diseases. Allergy RC581-607
spellingShingle	soybean oil intake fasting blood glucose inflammatory factors Agriculture (General) S1-972 Immunologic diseases. Allergy RC581-607 Xinli Pei Zhongguo Xie Jing Wang Kaiwen Shi Fei Han Aike Li Haiying Liu The effect of various intake levels of soybean oil on blood glucose and inflammation in mice
description	The effects of various intake levels of soybean oil on carbohydrate metabolism and inflammation in mice were studied. Mice were supplied with different diets, in which soybean oil provided 5, 10, 15, 20, 25, and 30% of total energy. Blood glucose indices, blood fat indices, inflammatory factors, and gene expression of insulin receptor substrates 1 and 2 Insulin receptor substrate 1 (IRS1) and Insulin receptor substrate 2 (IRS2) were analyzed. The results showed that higher intake of soybean oil can lead to excessive weight gain, higher levels of fasting blood glucose and serum insulin, increased levels of tumor necrosis factor-α, interleukin 6, hyper-sensitive C-reactive protein, and reduced expression of IRS1 and IRS2 mRNA. Primarily, we found that reduced intake of soybean oil led to a similar trend to that of a high soybean oil diet. The optimal intake of soybean oil, as supplied in the diet, was about 15–20%.
format	article
author	Xinli Pei Zhongguo Xie Jing Wang Kaiwen Shi Fei Han Aike Li Haiying Liu
author_facet	Xinli Pei Zhongguo Xie Jing Wang Kaiwen Shi Fei Han Aike Li Haiying Liu
author_sort	Xinli Pei
title	The effect of various intake levels of soybean oil on blood glucose and inflammation in mice
title_short	The effect of various intake levels of soybean oil on blood glucose and inflammation in mice
title_full	The effect of various intake levels of soybean oil on blood glucose and inflammation in mice
title_fullStr	The effect of various intake levels of soybean oil on blood glucose and inflammation in mice
title_full_unstemmed	The effect of various intake levels of soybean oil on blood glucose and inflammation in mice
title_sort	effect of various intake levels of soybean oil on blood glucose and inflammation in mice
publisher	Taylor & Francis Group
publishDate	2018
url	https://doaj.org/article/3d3848c6e819482a951998ac829b865c
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The effect of various intake levels of soybean oil on blood glucose and inflammation in mice

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