Lung collagens perpetuate pulmonary fibrosis via CD204 and M2 macrophage activation.
Idiopathic pulmonary fibrosis is characterized by abundant collagen production and accumulation of alternatively activated macrophages (M2) in the lower respiratory tract. Mechanisms as to how alveolar macrophages are activated by collagen breakdown products are unknown. Alveolar macrophages were ob...
Guardado en:
Autores principales: | Mirjam Stahl, Jonas Schupp, Benedikt Jäger, Michael Schmid, Gernot Zissel, Joachim Müller-Quernheim, Antje Prasse |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/3d3a7362be2d4a44a0c34060639c3e6c |
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