A novel BMP-2–loaded hydroxyapatite/beta-tricalcium phosphate microsphere/hydrogel composite for bone regeneration

A novel BMP-2–loaded hydroxyapatite/beta-tricalcium phosphate microsphere/hydrogel composite for bone regeneration

Abstract Although bone morphogenetic protein (BMP) has potent osteoinductivity, the potential adverse events attributed to its burst release prevent its widespread clinical application. Therefore, there is a strong need for BMP delivery systems that maximize osteoinductivity while preventing adverse...

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Autores principales: Daisuke Tateiwa, Shinichi Nakagawa, Hiroyuki Tsukazaki, Rintaro Okada, Joe Kodama, Junichi Kushioka, Zeynep Bal, Yuichiro Ukon, Hiromasa Hirai, Takashi Kaito
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/3d434f4005814c69917236e42c7b0c5c
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