Major discrepancies between clinical and postmortem diagnoses in critically ill cancer patients: Is autopsy still useful?

Objective: Describe the major discrepancies between the clinical and postmortem findings in critically ill cancer patients admitted to the medical intensive care unit (MICU). Materials and Methods: Retrospectively review of the medical records of all cancer patients who were admitted to the MICU and...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Owais Khawaja, Mohammad Khalil, Omar Zmeili, Ayman O Soubani
Formato:	article
Lenguaje:	EN
Publicado:	Thieme Medical and Scientific Publishers Pvt. Ltd. 2013
Materias:	autopsy cancer critical care Medicine R
Acceso en línea:	https://doaj.org/article/3d4452d54e2d4f39bb95790557095466
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:3d4452d54e2d4f39bb95790557095466
record_format	dspace
spelling	oai:doaj.org-article:3d4452d54e2d4f39bb957905570954662021-12-02T16:24:51ZMajor discrepancies between clinical and postmortem diagnoses in critically ill cancer patients: Is autopsy still useful?2231-07702249-446410.4103/2231-0770.118460https://doaj.org/article/3d4452d54e2d4f39bb957905570954662013-07-01T00:00:00Zhttp://www.thieme-connect.de/DOI/DOI?10.4103/2231-0770.118460https://doaj.org/toc/2231-0770https://doaj.org/toc/2249-4464Objective: Describe the major discrepancies between the clinical and postmortem findings in critically ill cancer patients admitted to the medical intensive care unit (MICU). Materials and Methods: Retrospectively review of the medical records of all cancer patients who were admitted to the MICU and underwent postmortem examination over 6 year period. The records were reviewed for demographics, Acute Physiology and Chronic Health Evaluation (APACHE) II score, clinical cause of death, and postmortem findings. Results: There were 70 patients who had complete medical records. Mean age was 54.7 years (standard deviation (SD) ±14.8 years). Twenty-six patients had hematopoeitic stem cell transplantation (group I), 21 patients had hematological malignancies (group II), and 23 patients had solid malignancies (group III). The APACHE II score on admission to the MICU was 24.2 ± 8.0. Sixty-seven patients were mechanically ventilated, and the MICU stay was (mean ± SD) 9.0 ± 11.6 days. Major discrepancies between the clinical and postmortem diagnoses (Goldman classes I and II) were detected in 15 patients (21%). The most common missed diagnoses were aspergillosis, pulmonary embolism, and cancer recurrence. There were no differences between groups regarding the rate of major discrepancies. Conclusion: Despite the advances in the diagnosis and treatment of critically ill cancer patients, autopsies continue to show major discrepancies between the clinical and postmortem diagnoses. Autopsy is still useful in this patient population.Owais KhawajaMohammad KhalilOmar ZmeiliAyman O SoubaniThieme Medical and Scientific Publishers Pvt. Ltd.articleautopsycancercritical careMedicineRENAvicenna Journal of Medicine, Vol 03, Iss 03, Pp 63-67 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	autopsy cancer critical care Medicine R
spellingShingle	autopsy cancer critical care Medicine R Owais Khawaja Mohammad Khalil Omar Zmeili Ayman O Soubani Major discrepancies between clinical and postmortem diagnoses in critically ill cancer patients: Is autopsy still useful?
description	Objective: Describe the major discrepancies between the clinical and postmortem findings in critically ill cancer patients admitted to the medical intensive care unit (MICU). Materials and Methods: Retrospectively review of the medical records of all cancer patients who were admitted to the MICU and underwent postmortem examination over 6 year period. The records were reviewed for demographics, Acute Physiology and Chronic Health Evaluation (APACHE) II score, clinical cause of death, and postmortem findings. Results: There were 70 patients who had complete medical records. Mean age was 54.7 years (standard deviation (SD) ±14.8 years). Twenty-six patients had hematopoeitic stem cell transplantation (group I), 21 patients had hematological malignancies (group II), and 23 patients had solid malignancies (group III). The APACHE II score on admission to the MICU was 24.2 ± 8.0. Sixty-seven patients were mechanically ventilated, and the MICU stay was (mean ± SD) 9.0 ± 11.6 days. Major discrepancies between the clinical and postmortem diagnoses (Goldman classes I and II) were detected in 15 patients (21%). The most common missed diagnoses were aspergillosis, pulmonary embolism, and cancer recurrence. There were no differences between groups regarding the rate of major discrepancies. Conclusion: Despite the advances in the diagnosis and treatment of critically ill cancer patients, autopsies continue to show major discrepancies between the clinical and postmortem diagnoses. Autopsy is still useful in this patient population.
format	article
author	Owais Khawaja Mohammad Khalil Omar Zmeili Ayman O Soubani
author_facet	Owais Khawaja Mohammad Khalil Omar Zmeili Ayman O Soubani
author_sort	Owais Khawaja
title	Major discrepancies between clinical and postmortem diagnoses in critically ill cancer patients: Is autopsy still useful?
title_short	Major discrepancies between clinical and postmortem diagnoses in critically ill cancer patients: Is autopsy still useful?
title_full	Major discrepancies between clinical and postmortem diagnoses in critically ill cancer patients: Is autopsy still useful?
title_fullStr	Major discrepancies between clinical and postmortem diagnoses in critically ill cancer patients: Is autopsy still useful?
title_full_unstemmed	Major discrepancies between clinical and postmortem diagnoses in critically ill cancer patients: Is autopsy still useful?
title_sort	major discrepancies between clinical and postmortem diagnoses in critically ill cancer patients: is autopsy still useful?
publisher	Thieme Medical and Scientific Publishers Pvt. Ltd.
publishDate	2013
url	https://doaj.org/article/3d4452d54e2d4f39bb95790557095466
work_keys_str_mv	AT owaiskhawaja majordiscrepanciesbetweenclinicalandpostmortemdiagnosesincriticallyillcancerpatientsisautopsystilluseful AT mohammadkhalil majordiscrepanciesbetweenclinicalandpostmortemdiagnosesincriticallyillcancerpatientsisautopsystilluseful AT omarzmeili majordiscrepanciesbetweenclinicalandpostmortemdiagnosesincriticallyillcancerpatientsisautopsystilluseful AT aymanosoubani majordiscrepanciesbetweenclinicalandpostmortemdiagnosesincriticallyillcancerpatientsisautopsystilluseful
_version_	1718384104819392512

Major discrepancies between clinical and postmortem diagnoses in critically ill cancer patients: Is autopsy still useful?

Ejemplares similares