Right and left ventricular function and flow quantification in pediatric patients with repaired tetralogy of Fallot using four-dimensional flow magnetic resonance imaging

Abstract Background To assess the accuracy and reproducibility of right ventricular (RV) and left ventricular (LV) function and flow measurements in children with repaired tetralogy of Fallot (rTOF) using four-dimensional (4D) flow, compared with conventional two-dimensional (2D) magnetic resonance...

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Autores principales:	Xiaofen Yao, Liwei Hu, Yafeng Peng, Fei Feng, Rongzhen Ouyang, Weihui Xie, Qian Wang, Aimin Sun, Yumin Zhong
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	4D flow Cardiac magnetic resonance Repaired tetralogy of Fallot Medical technology R855-855.5
Acceso en línea:	https://doaj.org/article/3d5058ed06804e609f7558d81c36b6e3
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spelling	oai:doaj.org-article:3d5058ed06804e609f7558d81c36b6e32021-11-08T11:05:11ZRight and left ventricular function and flow quantification in pediatric patients with repaired tetralogy of Fallot using four-dimensional flow magnetic resonance imaging10.1186/s12880-021-00693-21471-2342https://doaj.org/article/3d5058ed06804e609f7558d81c36b6e32021-10-01T00:00:00Zhttps://doi.org/10.1186/s12880-021-00693-2https://doaj.org/toc/1471-2342Abstract Background To assess the accuracy and reproducibility of right ventricular (RV) and left ventricular (LV) function and flow measurements in children with repaired tetralogy of Fallot (rTOF) using four-dimensional (4D) flow, compared with conventional two-dimensional (2D) magnetic resonance imaging (MRI) sequences. Methods Thirty pediatric patients with rTOF were retrospectively enrolled to undergo 2D balanced steady-state free precession cine (2D b-SSFP cine), 2D phase contrast (PC), and 4D flow cardiac MRI. LV and RV volumes and flow in the ascending aorta (AAO) and main pulmonary artery (MPA) were quantified. Pearson’s or Spearman’s correlation tests, paired t-tests, the Wilcoxon signed-rank test, Bland–Altman analysis, and intraclass correlation coefficients (ICC) were performed. Results The 4D flow scan time was shorter compared with 2D sequences (P < 0.001). The biventricular volumes between 4D flow and 2D b-SSFP cine had no significant differences (P > 0.05), and showed strong correlations (r > 0.90, P < 0.001) and good consistency. The flow measurements of the AAO and MPA between 4D flow and 2D PC showed moderate to good correlations (r > 0.60, P < 0.001). There was good internal consistency in cardiac output. There was good intraobserver and interobserver biventricular function agreement (ICC > 0.85). Conclusions RV and LV function and flow quantification in pediatric patients with rTOF using 4D flow MRI can be measured accurately and reproducibly compared to those with conventional 2D sequences.Xiaofen YaoLiwei HuYafeng PengFei FengRongzhen OuyangWeihui XieQian WangAimin SunYumin ZhongBMCarticle4D flowCardiac magnetic resonanceRepaired tetralogy of FallotMedical technologyR855-855.5ENBMC Medical Imaging, Vol 21, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	4D flow Cardiac magnetic resonance Repaired tetralogy of Fallot Medical technology R855-855.5
spellingShingle	4D flow Cardiac magnetic resonance Repaired tetralogy of Fallot Medical technology R855-855.5 Xiaofen Yao Liwei Hu Yafeng Peng Fei Feng Rongzhen Ouyang Weihui Xie Qian Wang Aimin Sun Yumin Zhong Right and left ventricular function and flow quantification in pediatric patients with repaired tetralogy of Fallot using four-dimensional flow magnetic resonance imaging
description	Abstract Background To assess the accuracy and reproducibility of right ventricular (RV) and left ventricular (LV) function and flow measurements in children with repaired tetralogy of Fallot (rTOF) using four-dimensional (4D) flow, compared with conventional two-dimensional (2D) magnetic resonance imaging (MRI) sequences. Methods Thirty pediatric patients with rTOF were retrospectively enrolled to undergo 2D balanced steady-state free precession cine (2D b-SSFP cine), 2D phase contrast (PC), and 4D flow cardiac MRI. LV and RV volumes and flow in the ascending aorta (AAO) and main pulmonary artery (MPA) were quantified. Pearson’s or Spearman’s correlation tests, paired t-tests, the Wilcoxon signed-rank test, Bland–Altman analysis, and intraclass correlation coefficients (ICC) were performed. Results The 4D flow scan time was shorter compared with 2D sequences (P < 0.001). The biventricular volumes between 4D flow and 2D b-SSFP cine had no significant differences (P > 0.05), and showed strong correlations (r > 0.90, P < 0.001) and good consistency. The flow measurements of the AAO and MPA between 4D flow and 2D PC showed moderate to good correlations (r > 0.60, P < 0.001). There was good internal consistency in cardiac output. There was good intraobserver and interobserver biventricular function agreement (ICC > 0.85). Conclusions RV and LV function and flow quantification in pediatric patients with rTOF using 4D flow MRI can be measured accurately and reproducibly compared to those with conventional 2D sequences.
format	article
author	Xiaofen Yao Liwei Hu Yafeng Peng Fei Feng Rongzhen Ouyang Weihui Xie Qian Wang Aimin Sun Yumin Zhong
author_facet	Xiaofen Yao Liwei Hu Yafeng Peng Fei Feng Rongzhen Ouyang Weihui Xie Qian Wang Aimin Sun Yumin Zhong
author_sort	Xiaofen Yao
title	Right and left ventricular function and flow quantification in pediatric patients with repaired tetralogy of Fallot using four-dimensional flow magnetic resonance imaging
title_short	Right and left ventricular function and flow quantification in pediatric patients with repaired tetralogy of Fallot using four-dimensional flow magnetic resonance imaging
title_full	Right and left ventricular function and flow quantification in pediatric patients with repaired tetralogy of Fallot using four-dimensional flow magnetic resonance imaging
title_fullStr	Right and left ventricular function and flow quantification in pediatric patients with repaired tetralogy of Fallot using four-dimensional flow magnetic resonance imaging
title_full_unstemmed	Right and left ventricular function and flow quantification in pediatric patients with repaired tetralogy of Fallot using four-dimensional flow magnetic resonance imaging
title_sort	right and left ventricular function and flow quantification in pediatric patients with repaired tetralogy of fallot using four-dimensional flow magnetic resonance imaging
publisher	BMC
publishDate	2021
url	https://doaj.org/article/3d5058ed06804e609f7558d81c36b6e3
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Right and left ventricular function and flow quantification in pediatric patients with repaired tetralogy of Fallot using four-dimensional flow magnetic resonance imaging

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