Coding and decoding libraries of sequence-defined functional copolymers synthesized via photoligation

Controlling the molecular sequence of polymers and oligomers is a challenging task. Here the authors use a photoligation approach to synthesise macromolecules with functionality at defined positions throughout the chain, and additionally decode the sequence information via tandem mass spectrometry.

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Autores principales: Nicolas Zydziak, Waldemar Konrad, Florian Feist, Sergii Afonin, Steffen Weidner, Christopher Barner-Kowollik
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/3d51d8a57ddc4cbd928a010b0c6f25d8
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Sumario:Controlling the molecular sequence of polymers and oligomers is a challenging task. Here the authors use a photoligation approach to synthesise macromolecules with functionality at defined positions throughout the chain, and additionally decode the sequence information via tandem mass spectrometry.