Hypoxia and hypoxia inducible factor-1α are required for normal endometrial repair during menstruation

About a quarter of pre-menopausal women will suffer from heavy menstrual bleeding in their lives. Here, Maybin and colleagues show hypoxia and subsequent activation of HIF-1α during menses are required for normal endometrial repair, and identify pharmacological stabilisation of HIF-1α as a potential...

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Autores principales: Jacqueline A. Maybin, Alison A. Murray, Philippa T. K. Saunders, Nikhil Hirani, Peter Carmeliet, Hilary O. D. Critchley
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/3d625696cf6342b79ac265446a69ab16
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