Peripheral blood leukocyte telomere length as a possible prognostic marker for the development of atrial fibrillation

Atrial fibrillation is one of the most common heart rhythm disorders. The most prominent risk factor for atrial fibrillation is advanced age. Population ageing contributes to an increase in both the prevalence of this pathology and socio-economic burden of the disease for society in general and the...

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Autores principales:	Svetlana Yu. Nikulina, Ksenya Yu. Shihkova, Vladimir A. Shulman, Anna A. Chernova, Vladimir N. Maksimov
Formato:	article
Lenguaje:	EN RU
Publicado:	Concilium Medicum 2020
Materias:	atrial fibrillation telomers length of telomers of leucocytes length of telomers of myocytes of atrium radiofrequency catheter ablation clinical trials predictive markers Diseases of the circulatory (Cardiovascular) system RC666-701 Diseases of the endocrine glands. Clinical endocrinology RC648-665
Acceso en línea:	https://doaj.org/article/3d7546de5edd4b1f99127138331fbc91
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spelling	oai:doaj.org-article:3d7546de5edd4b1f99127138331fbc912021-12-01T22:07:01ZPeripheral blood leukocyte telomere length as a possible prognostic marker for the development of atrial fibrillation2221-71852658-570710.26442/22217185.2020.2.200227https://doaj.org/article/3d7546de5edd4b1f99127138331fbc912020-09-01T00:00:00Zhttps://cardiosomatics.orscience.ru/2221-7185/article/viewFile/46032/31035https://doaj.org/toc/2221-7185https://doaj.org/toc/2658-5707Atrial fibrillation is one of the most common heart rhythm disorders. The most prominent risk factor for atrial fibrillation is advanced age. Population ageing contributes to an increase in both the prevalence of this pathology and socio-economic burden of the disease for society in general and the patient in particular. Adequate therapy and prevention of atrial fibrillation requires the search for novel prognostic risk markers for disease development, progression, and patients response to therapy. One of these markers is the length of telomeres structures at the ends of chromosomes that protect them from degradation during cell division. The article provides an overview of world studies, both confirming and disproving the role of leukocyte telomere length in atrial fibrillation development.Svetlana Yu. NikulinaKsenya Yu. ShihkovaVladimir A. ShulmanAnna A. ChernovaVladimir N. MaksimovConcilium Medicumarticleatrial fibrillationtelomerslength of telomers of leucocyteslength of telomers of myocytes of atriumradiofrequency catheter ablationclinical trialspredictive markersDiseases of the circulatory (Cardiovascular) systemRC666-701Diseases of the endocrine glands. Clinical endocrinologyRC648-665ENRUКардиоСоматика, Vol 11, Iss 2, Pp 50-54 (2020)
institution	DOAJ
collection	DOAJ
language	EN RU
topic	atrial fibrillation telomers length of telomers of leucocytes length of telomers of myocytes of atrium radiofrequency catheter ablation clinical trials predictive markers Diseases of the circulatory (Cardiovascular) system RC666-701 Diseases of the endocrine glands. Clinical endocrinology RC648-665
spellingShingle	atrial fibrillation telomers length of telomers of leucocytes length of telomers of myocytes of atrium radiofrequency catheter ablation clinical trials predictive markers Diseases of the circulatory (Cardiovascular) system RC666-701 Diseases of the endocrine glands. Clinical endocrinology RC648-665 Svetlana Yu. Nikulina Ksenya Yu. Shihkova Vladimir A. Shulman Anna A. Chernova Vladimir N. Maksimov Peripheral blood leukocyte telomere length as a possible prognostic marker for the development of atrial fibrillation
description	Atrial fibrillation is one of the most common heart rhythm disorders. The most prominent risk factor for atrial fibrillation is advanced age. Population ageing contributes to an increase in both the prevalence of this pathology and socio-economic burden of the disease for society in general and the patient in particular. Adequate therapy and prevention of atrial fibrillation requires the search for novel prognostic risk markers for disease development, progression, and patients response to therapy. One of these markers is the length of telomeres structures at the ends of chromosomes that protect them from degradation during cell division. The article provides an overview of world studies, both confirming and disproving the role of leukocyte telomere length in atrial fibrillation development.
format	article
author	Svetlana Yu. Nikulina Ksenya Yu. Shihkova Vladimir A. Shulman Anna A. Chernova Vladimir N. Maksimov
author_facet	Svetlana Yu. Nikulina Ksenya Yu. Shihkova Vladimir A. Shulman Anna A. Chernova Vladimir N. Maksimov
author_sort	Svetlana Yu. Nikulina
title	Peripheral blood leukocyte telomere length as a possible prognostic marker for the development of atrial fibrillation
title_short	Peripheral blood leukocyte telomere length as a possible prognostic marker for the development of atrial fibrillation
title_full	Peripheral blood leukocyte telomere length as a possible prognostic marker for the development of atrial fibrillation
title_fullStr	Peripheral blood leukocyte telomere length as a possible prognostic marker for the development of atrial fibrillation
title_full_unstemmed	Peripheral blood leukocyte telomere length as a possible prognostic marker for the development of atrial fibrillation
title_sort	peripheral blood leukocyte telomere length as a possible prognostic marker for the development of atrial fibrillation
publisher	Concilium Medicum
publishDate	2020
url	https://doaj.org/article/3d7546de5edd4b1f99127138331fbc91
work_keys_str_mv	AT svetlanayunikulina peripheralbloodleukocytetelomerelengthasapossibleprognosticmarkerforthedevelopmentofatrialfibrillation AT ksenyayushihkova peripheralbloodleukocytetelomerelengthasapossibleprognosticmarkerforthedevelopmentofatrialfibrillation AT vladimirashulman peripheralbloodleukocytetelomerelengthasapossibleprognosticmarkerforthedevelopmentofatrialfibrillation AT annaachernova peripheralbloodleukocytetelomerelengthasapossibleprognosticmarkerforthedevelopmentofatrialfibrillation AT vladimirnmaksimov peripheralbloodleukocytetelomerelengthasapossibleprognosticmarkerforthedevelopmentofatrialfibrillation
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Peripheral blood leukocyte telomere length as a possible prognostic marker for the development of atrial fibrillation

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