ß-arrestin 2 germline knockout does not attenuate opioid respiratory depression

Opioids are perhaps the most effective analgesics in medicine. However, between 1999 and 2018, over 400,000 people in the United States died from opioid overdose. Excessive opioids make breathing lethally slow and shallow, a side-effect called opioid-induced respiratory depression. This doubled-edge...

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Autores principales: Iris Bachmutsky, Xin Paul Wei, Adelae Durand, Kevin Yackle
Formato: article
Lenguaje:EN
Publicado: eLife Sciences Publications Ltd 2021
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Acceso en línea:https://doaj.org/article/3d779d06f0444987a64d0cd42796b504
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