Non-Coding RNAs as Regulators of Myogenesis and Postexercise Muscle Regeneration

miRNAs and lncRNAs do not encode proteins, but they play an important role in the regulation of gene expression. They differ in length, biogenesis, and mode of action. In this work, we focus on the selected miRNAs and lncRNAs involved in the regulation of myogenesis and muscle regeneration. We prese...

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Autores principales: Karolina Archacka, Maria A. Ciemerych, Anita Florkowska, Karolina Romanczuk
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/3d888dbf737e4ca8b65ec1537e11948a
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spelling oai:doaj.org-article:3d888dbf737e4ca8b65ec1537e11948a2021-11-11T17:03:04ZNon-Coding RNAs as Regulators of Myogenesis and Postexercise Muscle Regeneration10.3390/ijms2221115681422-00671661-6596https://doaj.org/article/3d888dbf737e4ca8b65ec1537e11948a2021-10-01T00:00:00Zhttps://www.mdpi.com/1422-0067/22/21/11568https://doaj.org/toc/1661-6596https://doaj.org/toc/1422-0067miRNAs and lncRNAs do not encode proteins, but they play an important role in the regulation of gene expression. They differ in length, biogenesis, and mode of action. In this work, we focus on the selected miRNAs and lncRNAs involved in the regulation of myogenesis and muscle regeneration. We present selected miRNAs and lncRNAs that have been shown to control myogenic differentiation and show that manipulation of their levels could be used to improve myogenic differentiation of various types of stem and progenitor cells. Finally, we discuss how physical activity affects miRNA and lncRNA expression and how it affects muscle well-being.Karolina ArchackaMaria A. CiemerychAnita FlorkowskaKarolina RomanczukMDPI AGarticlemammalshumanmousemiRNAlncRNAmyogenesisBiology (General)QH301-705.5ChemistryQD1-999ENInternational Journal of Molecular Sciences, Vol 22, Iss 11568, p 11568 (2021)
institution DOAJ
collection DOAJ
language EN
topic mammals
human
mouse
miRNA
lncRNA
myogenesis
Biology (General)
QH301-705.5
Chemistry
QD1-999
spellingShingle mammals
human
mouse
miRNA
lncRNA
myogenesis
Biology (General)
QH301-705.5
Chemistry
QD1-999
Karolina Archacka
Maria A. Ciemerych
Anita Florkowska
Karolina Romanczuk
Non-Coding RNAs as Regulators of Myogenesis and Postexercise Muscle Regeneration
description miRNAs and lncRNAs do not encode proteins, but they play an important role in the regulation of gene expression. They differ in length, biogenesis, and mode of action. In this work, we focus on the selected miRNAs and lncRNAs involved in the regulation of myogenesis and muscle regeneration. We present selected miRNAs and lncRNAs that have been shown to control myogenic differentiation and show that manipulation of their levels could be used to improve myogenic differentiation of various types of stem and progenitor cells. Finally, we discuss how physical activity affects miRNA and lncRNA expression and how it affects muscle well-being.
format article
author Karolina Archacka
Maria A. Ciemerych
Anita Florkowska
Karolina Romanczuk
author_facet Karolina Archacka
Maria A. Ciemerych
Anita Florkowska
Karolina Romanczuk
author_sort Karolina Archacka
title Non-Coding RNAs as Regulators of Myogenesis and Postexercise Muscle Regeneration
title_short Non-Coding RNAs as Regulators of Myogenesis and Postexercise Muscle Regeneration
title_full Non-Coding RNAs as Regulators of Myogenesis and Postexercise Muscle Regeneration
title_fullStr Non-Coding RNAs as Regulators of Myogenesis and Postexercise Muscle Regeneration
title_full_unstemmed Non-Coding RNAs as Regulators of Myogenesis and Postexercise Muscle Regeneration
title_sort non-coding rnas as regulators of myogenesis and postexercise muscle regeneration
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/3d888dbf737e4ca8b65ec1537e11948a
work_keys_str_mv AT karolinaarchacka noncodingrnasasregulatorsofmyogenesisandpostexercisemuscleregeneration
AT mariaaciemerych noncodingrnasasregulatorsofmyogenesisandpostexercisemuscleregeneration
AT anitaflorkowska noncodingrnasasregulatorsofmyogenesisandpostexercisemuscleregeneration
AT karolinaromanczuk noncodingrnasasregulatorsofmyogenesisandpostexercisemuscleregeneration
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