Identification, replication, and functional fine-mapping of expression quantitative trait loci in primary human liver tissue.

Identification, replication, and functional fine-mapping of expression quantitative trait loci in primary human liver tissue.

The discovery of expression quantitative trait loci ("eQTLs") can help to unravel genetic contributions to complex traits. We identified genetic determinants of human liver gene expression variation using two independent collections of primary tissue profiled with Agilent (n = 206) and Ill...

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Autores principales: Federico Innocenti, Gregory M Cooper, Ian B Stanaway, Eric R Gamazon, Joshua D Smith, Snezana Mirkov, Jacqueline Ramirez, Wanqing Liu, Yvonne S Lin, Cliona Moloney, Shelly Force Aldred, Nathan D Trinklein, Erin Schuetz, Deborah A Nickerson, Ken E Thummel, Mark J Rieder, Allan E Rettie, Mark J Ratain, Nancy J Cox, Christopher D Brown
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Genetics
QH426-470
Acceso en línea:https://doaj.org/article/3d934a1f80b8416d99b7b08cd2c4008a
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