Transcriptional inhibition by CDK7/9 inhibitor SNS-032 suppresses tumor growth and metastasis in esophageal squamous cell carcinoma

Abstract Metastasis is one of most lethal causes that confer a poor prognosis of patients with esophageal squamous cell carcinoma (ESCC), whereas there is no available target drug for metastatic ESCC currently. In this study, we aimed to determine whether the transcriptional inhibition by CDK7/9 inh...

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Autores principales: Huishan Zeng, Huiru Yang, Yifan Song, Dong Fang, Liang Chen, Zhijun Zhao, Chaojie Wang, Songqiang Xie
Formato: article
Lenguaje:EN
Publicado: Nature Publishing Group 2021
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Acceso en línea:https://doaj.org/article/3d94eb2c53144a038ade89d1a6833998
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