Transcriptional inhibition by CDK7/9 inhibitor SNS-032 suppresses tumor growth and metastasis in esophageal squamous cell carcinoma
Abstract Metastasis is one of most lethal causes that confer a poor prognosis of patients with esophageal squamous cell carcinoma (ESCC), whereas there is no available target drug for metastatic ESCC currently. In this study, we aimed to determine whether the transcriptional inhibition by CDK7/9 inh...
Guardado en:
Autores principales: | Huishan Zeng, Huiru Yang, Yifan Song, Dong Fang, Liang Chen, Zhijun Zhao, Chaojie Wang, Songqiang Xie |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Publishing Group
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/3d94eb2c53144a038ade89d1a6833998 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Hippo signaling suppresses tumor cell metastasis via a Yki-Src42A positive feedback loop
por: Yan Ding, et al.
Publicado: (2021) -
Nerve growth factor promotes lysyl oxidase-dependent chondrosarcoma cell metastasis by suppressing miR-149-5p synthesis
por: Huey-En Tzeng, et al.
Publicado: (2021) -
Correction to: RNA-binding protein SORBS2 suppresses clear cell renal cell carcinoma metastasis by enhancing MTUS1 mRNA stability
por: Qi Lv, et al.
Publicado: (2021) -
Circ_0058106 promotes proliferation, metastasis and EMT process by regulating Wnt2b/β-catenin/c-Myc pathway through miR-185-3p in hypopharyngeal squamous cell carcinoma
por: Ce Li, et al.
Publicado: (2021) -
ONECUT2 facilitates hepatocellular carcinoma metastasis by transcriptionally upregulating FGF2 and ACLY
por: Danfei Liu, et al.
Publicado: (2021)