Reversibility of Age-related Oxidized Free NADH Redox States in Alzheimer’s Disease Neurons by Imposed External Cys/CySS Redox Shifts
Abstract Redox systems including extracellular cysteine/cystine (Cys/CySS), intracellular glutathione/oxidized glutathione (GSH/GSSG) and nicotinamide adenine dinucleotide reduced/oxidized forms (NADH/NAD+) are critical for maintaining redox homeostasis. Aging as a major risk factor for Alzheimer’s...
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Auteurs principaux: | Yue Dong, Sara Sameni, Michelle A. Digman, Gregory J. Brewer |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2019
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Sujets: | |
Accès en ligne: | https://doaj.org/article/3d994a935b6545bf8db9f5135a0b2f0d |
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