Integration of 3D printing technology in pharmaceutical compounding: Progress, prospects, and challenges

ABSTRACT: A significant limitation of current medication development and usage is the reliance on the 'one-size-fits-all' approach. 3D printing technology is an innovative strategy for customizing medication design and preparation. In this review, we highlighted the potential of 3D printin...

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Autores principales:	Larissa A. Melnyk, Moses O. Oyewumi
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	3D printing technology Medicine Pharmacy 3D Printers Drug delivery Medical technology R855-855.5
Acceso en línea:	https://doaj.org/article/3da8678f475841119400a9678e56aab0
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spelling	oai:doaj.org-article:3da8678f475841119400a9678e56aab02021-11-24T04:35:13ZIntegration of 3D printing technology in pharmaceutical compounding: Progress, prospects, and challenges2666-964110.1016/j.stlm.2021.100035https://doaj.org/article/3da8678f475841119400a9678e56aab02021-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2666964121000308https://doaj.org/toc/2666-9641ABSTRACT: A significant limitation of current medication development and usage is the reliance on the 'one-size-fits-all' approach. 3D printing technology is an innovative strategy for customizing medication design and preparation. In this review, we highlighted the potential of 3D printing of medications as an effective strategy to achieve personalized precision medicines. Particular attention was paid to possible integration of 3D printing technology in pharmaceutical compounding process to improve flexibility, efficiency, safety, quality, trust, and utility. Significant barriers to overcome include: (i) insufficient training on 3D printing compounding and regulation requirements, (ii) limited choices of 3D printers and approved excipients that are amenable to routine pharmacy operations, and (iii) lack of efficient medication verification techniques to ascertain that the intended medication qualities and characteristics are achieved through 3D printing customization.Larissa A. MelnykMoses O. OyewumiElsevierarticle3D printing technologyMedicinePharmacy3D PrintersDrug deliveryMedical technologyR855-855.5ENAnnals of 3D Printed Medicine, Vol 4, Iss , Pp 100035- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	3D printing technology Medicine Pharmacy 3D Printers Drug delivery Medical technology R855-855.5
spellingShingle	3D printing technology Medicine Pharmacy 3D Printers Drug delivery Medical technology R855-855.5 Larissa A. Melnyk Moses O. Oyewumi Integration of 3D printing technology in pharmaceutical compounding: Progress, prospects, and challenges
description	ABSTRACT: A significant limitation of current medication development and usage is the reliance on the 'one-size-fits-all' approach. 3D printing technology is an innovative strategy for customizing medication design and preparation. In this review, we highlighted the potential of 3D printing of medications as an effective strategy to achieve personalized precision medicines. Particular attention was paid to possible integration of 3D printing technology in pharmaceutical compounding process to improve flexibility, efficiency, safety, quality, trust, and utility. Significant barriers to overcome include: (i) insufficient training on 3D printing compounding and regulation requirements, (ii) limited choices of 3D printers and approved excipients that are amenable to routine pharmacy operations, and (iii) lack of efficient medication verification techniques to ascertain that the intended medication qualities and characteristics are achieved through 3D printing customization.
format	article
author	Larissa A. Melnyk Moses O. Oyewumi
author_facet	Larissa A. Melnyk Moses O. Oyewumi
author_sort	Larissa A. Melnyk
title	Integration of 3D printing technology in pharmaceutical compounding: Progress, prospects, and challenges
title_short	Integration of 3D printing technology in pharmaceutical compounding: Progress, prospects, and challenges
title_full	Integration of 3D printing technology in pharmaceutical compounding: Progress, prospects, and challenges
title_fullStr	Integration of 3D printing technology in pharmaceutical compounding: Progress, prospects, and challenges
title_full_unstemmed	Integration of 3D printing technology in pharmaceutical compounding: Progress, prospects, and challenges
title_sort	integration of 3d printing technology in pharmaceutical compounding: progress, prospects, and challenges
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/3da8678f475841119400a9678e56aab0
work_keys_str_mv	AT larissaamelnyk integrationof3dprintingtechnologyinpharmaceuticalcompoundingprogressprospectsandchallenges AT mosesooyewumi integrationof3dprintingtechnologyinpharmaceuticalcompoundingprogressprospectsandchallenges
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Integration of 3D printing technology in pharmaceutical compounding: Progress, prospects, and challenges

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