Infected erythrocyte-derived extracellular vesicles alter vascular function via regulatory Ago2-miRNA complexes in malaria
Inflammatory response to malaria pathogen Plasmodium falciparumcan be triggered by infected red blood cell-derived extracellular vesicles (EVs). This study shows these EVs contain functional microRNA-Argonaute 2 complex that modulates gene expression and alter vascular barrier properties.
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Nature Portfolio
2016
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oai:doaj.org-article:3dbc56a1b2a84b54b49094d3638bdf382021-12-02T17:32:21ZInfected erythrocyte-derived extracellular vesicles alter vascular function via regulatory Ago2-miRNA complexes in malaria10.1038/ncomms127272041-1723https://doaj.org/article/3dbc56a1b2a84b54b49094d3638bdf382016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms12727https://doaj.org/toc/2041-1723Inflammatory response to malaria pathogen Plasmodium falciparumcan be triggered by infected red blood cell-derived extracellular vesicles (EVs). This study shows these EVs contain functional microRNA-Argonaute 2 complex that modulates gene expression and alter vascular barrier properties.Pierre-Yves MantelDaisy HjelmqvistMichael WalchSolange Kharoubi-HessSandra NilssonDeepali RavelMarina RibeiroChristof GrüringSiyuan MaPrasad PadmanabhanAlexander TrachtenbergJohan AnkarklevNicolas M. BrancucciCurtis HuttenhowerManoj T. DuraisinghIonita GhiranWinston P. KuoLuis FilgueiraRoberta MartinelliMatthias MartiNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-15 (2016) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Pierre-Yves Mantel Daisy Hjelmqvist Michael Walch Solange Kharoubi-Hess Sandra Nilsson Deepali Ravel Marina Ribeiro Christof Grüring Siyuan Ma Prasad Padmanabhan Alexander Trachtenberg Johan Ankarklev Nicolas M. Brancucci Curtis Huttenhower Manoj T. Duraisingh Ionita Ghiran Winston P. Kuo Luis Filgueira Roberta Martinelli Matthias Marti Infected erythrocyte-derived extracellular vesicles alter vascular function via regulatory Ago2-miRNA complexes in malaria |
| description |
Inflammatory response to malaria pathogen Plasmodium falciparumcan be triggered by infected red blood cell-derived extracellular vesicles (EVs). This study shows these EVs contain functional microRNA-Argonaute 2 complex that modulates gene expression and alter vascular barrier properties. |
| format |
article |
| author |
Pierre-Yves Mantel Daisy Hjelmqvist Michael Walch Solange Kharoubi-Hess Sandra Nilsson Deepali Ravel Marina Ribeiro Christof Grüring Siyuan Ma Prasad Padmanabhan Alexander Trachtenberg Johan Ankarklev Nicolas M. Brancucci Curtis Huttenhower Manoj T. Duraisingh Ionita Ghiran Winston P. Kuo Luis Filgueira Roberta Martinelli Matthias Marti |
| author_facet |
Pierre-Yves Mantel Daisy Hjelmqvist Michael Walch Solange Kharoubi-Hess Sandra Nilsson Deepali Ravel Marina Ribeiro Christof Grüring Siyuan Ma Prasad Padmanabhan Alexander Trachtenberg Johan Ankarklev Nicolas M. Brancucci Curtis Huttenhower Manoj T. Duraisingh Ionita Ghiran Winston P. Kuo Luis Filgueira Roberta Martinelli Matthias Marti |
| author_sort |
Pierre-Yves Mantel |
| title |
Infected erythrocyte-derived extracellular vesicles alter vascular function via regulatory Ago2-miRNA complexes in malaria |
| title_short |
Infected erythrocyte-derived extracellular vesicles alter vascular function via regulatory Ago2-miRNA complexes in malaria |
| title_full |
Infected erythrocyte-derived extracellular vesicles alter vascular function via regulatory Ago2-miRNA complexes in malaria |
| title_fullStr |
Infected erythrocyte-derived extracellular vesicles alter vascular function via regulatory Ago2-miRNA complexes in malaria |
| title_full_unstemmed |
Infected erythrocyte-derived extracellular vesicles alter vascular function via regulatory Ago2-miRNA complexes in malaria |
| title_sort |
infected erythrocyte-derived extracellular vesicles alter vascular function via regulatory ago2-mirna complexes in malaria |
| publisher |
Nature Portfolio |
| publishDate |
2016 |
| url |
https://doaj.org/article/3dbc56a1b2a84b54b49094d3638bdf38 |
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