Olfactory expression of trace amine-associated receptors requires cooperative cis-acting enhancers
How olfactory sensory neurons express one allele of one TAAR gene is not well understood. Here the authors identify two cooperative cis-acting enhancers that govern TAAR gene choice and that share both similarities and differences with known olfactory enhancers.
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Nature Portfolio
2021
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oai:doaj.org-article:3dc899aecc0d45b2bae7c5766190b03d2021-12-02T17:23:15ZOlfactory expression of trace amine-associated receptors requires cooperative cis-acting enhancers10.1038/s41467-021-23824-32041-1723https://doaj.org/article/3dc899aecc0d45b2bae7c5766190b03d2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23824-3https://doaj.org/toc/2041-1723How olfactory sensory neurons express one allele of one TAAR gene is not well understood. Here the authors identify two cooperative cis-acting enhancers that govern TAAR gene choice and that share both similarities and differences with known olfactory enhancers.Ami ShahMadison RatkowskiAlessandro RosaPaul FeinsteinThomas BozzaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021) |
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Science Q Ami Shah Madison Ratkowski Alessandro Rosa Paul Feinstein Thomas Bozza Olfactory expression of trace amine-associated receptors requires cooperative cis-acting enhancers |
description |
How olfactory sensory neurons express one allele of one TAAR gene is not well understood. Here the authors identify two cooperative cis-acting enhancers that govern TAAR gene choice and that share both similarities and differences with known olfactory enhancers. |
format |
article |
author |
Ami Shah Madison Ratkowski Alessandro Rosa Paul Feinstein Thomas Bozza |
author_facet |
Ami Shah Madison Ratkowski Alessandro Rosa Paul Feinstein Thomas Bozza |
author_sort |
Ami Shah |
title |
Olfactory expression of trace amine-associated receptors requires cooperative cis-acting enhancers |
title_short |
Olfactory expression of trace amine-associated receptors requires cooperative cis-acting enhancers |
title_full |
Olfactory expression of trace amine-associated receptors requires cooperative cis-acting enhancers |
title_fullStr |
Olfactory expression of trace amine-associated receptors requires cooperative cis-acting enhancers |
title_full_unstemmed |
Olfactory expression of trace amine-associated receptors requires cooperative cis-acting enhancers |
title_sort |
olfactory expression of trace amine-associated receptors requires cooperative cis-acting enhancers |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/3dc899aecc0d45b2bae7c5766190b03d |
work_keys_str_mv |
AT amishah olfactoryexpressionoftraceamineassociatedreceptorsrequirescooperativecisactingenhancers AT madisonratkowski olfactoryexpressionoftraceamineassociatedreceptorsrequirescooperativecisactingenhancers AT alessandrorosa olfactoryexpressionoftraceamineassociatedreceptorsrequirescooperativecisactingenhancers AT paulfeinstein olfactoryexpressionoftraceamineassociatedreceptorsrequirescooperativecisactingenhancers AT thomasbozza olfactoryexpressionoftraceamineassociatedreceptorsrequirescooperativecisactingenhancers |
_version_ |
1718380962438447104 |