Mechanisms driving the antibacterial and antibiofilm properties of Hp1404 and its analogue peptides against multidrug-resistant Pseudomonas aeruginosa

Abstract Hp1404, identified from the venom of the scorpion Heterometrus petersii, displays antimicrobial activity with cytotoxicity. Several synthetic peptides were designed based on the parent peptide Hp1404 to reduce cytotoxicity and improve activity (deletion of glycine and phenylalanine, substit...

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Autores principales: Min Kyung Kim, Hee Kyoung Kang, Su Jin Ko, Min Ji Hong, Jeong Kyu Bang, Chang Ho Seo, Yoonkyung Park
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/3dcffcc10a094df7ae0b517f7a4d43bc
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