Mechanisms driving the antibacterial and antibiofilm properties of Hp1404 and its analogue peptides against multidrug-resistant Pseudomonas aeruginosa

Abstract Hp1404, identified from the venom of the scorpion Heterometrus petersii, displays antimicrobial activity with cytotoxicity. Several synthetic peptides were designed based on the parent peptide Hp1404 to reduce cytotoxicity and improve activity (deletion of glycine and phenylalanine, substit...

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Bibliographic Details
Main Authors: Min Kyung Kim, Hee Kyoung Kang, Su Jin Ko, Min Ji Hong, Jeong Kyu Bang, Chang Ho Seo, Yoonkyung Park
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
R
Q
Online Access:https://doaj.org/article/3dcffcc10a094df7ae0b517f7a4d43bc
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