Early combination therapy of empagliflozin and linagliptin exerts beneficial effects on pancreatic β cells in diabetic db/db mice

Early combination therapy of empagliflozin and linagliptin exerts beneficial effects on pancreatic β cells in diabetic db/db mice

Abstract Effects of combination therapy of dipeptidyl peptidase-4 (DPP-4) inhibitor and sodium-glucose co-transporter 2 (SGLT2) inhibitor on β-cells are still unclear, although combination agent of these two drugs has become common in clinical practice. Therefore, we aimed to elucidate the effects o...

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Bibliographic Details
Main Authors: Yoshiro Fushimi, Atsushi Obata, Junpei Sanada, Yuka Nogami, Tomoko Ikeda, Yuki Yamasaki, Yoshiyuki Obata, Masashi Shimoda, Shuhei Nakanishi, Tomoatsu Mune, Kohei Kaku, Hideaki Kaneto
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/3dd05362d0c04b16bbd3922fdc75d61f
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https://doaj.org/article/3dd05362d0c04b16bbd3922fdc75d61f

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