Combination immunotherapy with two attenuated Listeria strains carrying shuffled HPV-16 E6E7 protein causes tumor regression in a mouse tumor model

Abstract Cervical cancer continues to impose a heavy burden worldwide, and human papilloma virus (HPV) infection, especially persistent infection with type 16 (HPV-16), is known to be the primary etiological factor. Therapeutic vaccines are urgently needed because prophylactic vaccines are ineffecti...

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Autores principales: Lin Su, Yunwen Zhang, Xiang Zhang, Ting Liu, Sijing Liu, Yongyu Li, Mingjuan Jiang, Tian Tang, Haiqian Shen, Chuan Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/3dde4d541fec4fbb901c537c5f212352
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