Acute myocardial ischemia: changes of free circulating mtDNA level in blood after occlusion of the upper one-third left descending branch of the coronary artery

The aim of the present study is to analyze the dynamics of free circulating mtDNA level in blood after occlusion of the upper one-third left descending branch of the coronary artery. We showed that the concentration of free circulating mtDNA of blood tends to decrease 24 hours after ligation; it inc...

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Autores principales:	N. P. Sudakov, T. P. Popkova, A. I. Katyshev, O. A. Goldberg, M. A. Novikova, S. B. Nikiforov, B. G. Pushkarev, I. V. Klimenkov, S. A. Lepekhova, K. A. Apartsin, S. D. Ezhikeeva, M. N. Ten, Yu. M. Konstantinov
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2013
Materias:	occlusion of the left coronary artery myocardial ischemia mtdna level biomarkers of cardiomyocite cytolysis real time pcr Science Q
Acceso en línea:	https://doaj.org/article/3df5895331e240799c27ea9ad5814529
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spelling	oai:doaj.org-article:3df5895331e240799c27ea9ad58145292021-11-23T06:14:29ZAcute myocardial ischemia: changes of free circulating mtDNA level in blood after occlusion of the upper one-third left descending branch of the coronary artery2541-94202587-9596https://doaj.org/article/3df5895331e240799c27ea9ad58145292013-09-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1662https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The aim of the present study is to analyze the dynamics of free circulating mtDNA level in blood after occlusion of the upper one-third left descending branch of the coronary artery. We showed that the concentration of free circulating mtDNA of blood tends to decrease 24 hours after ligation; it increased and reached values close to control samples 48 and 72 hours after ligation. These data define the need in further investigation of the dynamics of this parameter during later periods of myocardial infarction modeling that will contribute to objective evaluation of its significance for acute myocardial damage diagnostics and prognosis.N. P. SudakovT. P. PopkovaA. I. KatyshevO. A. GoldbergM. A. NovikovaS. B. NikiforovB. G. PushkarevI. V. KlimenkovS. A. LepekhovaK. A. ApartsinS. D. EzhikeevaM. N. TenYu. M. KonstantinovScientific Сentre for Family Health and Human Reproduction Problemsarticleocclusion of the left coronary arterymyocardial ischemiamtdna levelbiomarkers of cardiomyocite cytolysisreal time pcrScienceQRUActa Biomedica Scientifica, Vol 0, Iss 5, Pp 150-153 (2013)
institution	DOAJ
collection	DOAJ
language	RU
topic	occlusion of the left coronary artery myocardial ischemia mtdna level biomarkers of cardiomyocite cytolysis real time pcr Science Q
spellingShingle	occlusion of the left coronary artery myocardial ischemia mtdna level biomarkers of cardiomyocite cytolysis real time pcr Science Q N. P. Sudakov T. P. Popkova A. I. Katyshev O. A. Goldberg M. A. Novikova S. B. Nikiforov B. G. Pushkarev I. V. Klimenkov S. A. Lepekhova K. A. Apartsin S. D. Ezhikeeva M. N. Ten Yu. M. Konstantinov Acute myocardial ischemia: changes of free circulating mtDNA level in blood after occlusion of the upper one-third left descending branch of the coronary artery
description	The aim of the present study is to analyze the dynamics of free circulating mtDNA level in blood after occlusion of the upper one-third left descending branch of the coronary artery. We showed that the concentration of free circulating mtDNA of blood tends to decrease 24 hours after ligation; it increased and reached values close to control samples 48 and 72 hours after ligation. These data define the need in further investigation of the dynamics of this parameter during later periods of myocardial infarction modeling that will contribute to objective evaluation of its significance for acute myocardial damage diagnostics and prognosis.
format	article
author	N. P. Sudakov T. P. Popkova A. I. Katyshev O. A. Goldberg M. A. Novikova S. B. Nikiforov B. G. Pushkarev I. V. Klimenkov S. A. Lepekhova K. A. Apartsin S. D. Ezhikeeva M. N. Ten Yu. M. Konstantinov
author_facet	N. P. Sudakov T. P. Popkova A. I. Katyshev O. A. Goldberg M. A. Novikova S. B. Nikiforov B. G. Pushkarev I. V. Klimenkov S. A. Lepekhova K. A. Apartsin S. D. Ezhikeeva M. N. Ten Yu. M. Konstantinov
author_sort	N. P. Sudakov
title	Acute myocardial ischemia: changes of free circulating mtDNA level in blood after occlusion of the upper one-third left descending branch of the coronary artery
title_short	Acute myocardial ischemia: changes of free circulating mtDNA level in blood after occlusion of the upper one-third left descending branch of the coronary artery
title_full	Acute myocardial ischemia: changes of free circulating mtDNA level in blood after occlusion of the upper one-third left descending branch of the coronary artery
title_fullStr	Acute myocardial ischemia: changes of free circulating mtDNA level in blood after occlusion of the upper one-third left descending branch of the coronary artery
title_full_unstemmed	Acute myocardial ischemia: changes of free circulating mtDNA level in blood after occlusion of the upper one-third left descending branch of the coronary artery
title_sort	acute myocardial ischemia: changes of free circulating mtdna level in blood after occlusion of the upper one-third left descending branch of the coronary artery
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2013
url	https://doaj.org/article/3df5895331e240799c27ea9ad5814529
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Acute myocardial ischemia: changes of free circulating mtDNA level in blood after occlusion of the upper one-third left descending branch of the coronary artery

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