Searching large-scale scRNA-seq databases via unbiased cell embedding with Cell BLAST

Searching large-scale scRNA-seq databases via unbiased cell embedding with Cell BLAST

Single-cell RNA-seq (scRNA-seq) is being widely used to resolve cellular heterogeneity. Here, the authors present a cell-querying method built on a neural network-based generative model and a customized cell-to-cell similarity metric.

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Zhi-Jie Cao, Lin Wei, Shen Lu, De-Chang Yang, Ge Gao
Format: article
Langue:EN
Publié: Nature Portfolio 2020
Sujets:
Science
Q
Accès en ligne:https://doaj.org/article/3e0cf5f83c044e5689b8ee6fcaa6bccd
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
id oai:doaj.org-article:3e0cf5f83c044e5689b8ee6fcaa6bccd
record_format dspace
spelling oai:doaj.org-article:3e0cf5f83c044e5689b8ee6fcaa6bccd2021-12-02T16:15:09ZSearching large-scale scRNA-seq databases via unbiased cell embedding with Cell BLAST10.1038/s41467-020-17281-72041-1723https://doaj.org/article/3e0cf5f83c044e5689b8ee6fcaa6bccd2020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17281-7https://doaj.org/toc/2041-1723Single-cell RNA-seq (scRNA-seq) is being widely used to resolve cellular heterogeneity. Here, the authors present a cell-querying method built on a neural network-based generative model and a customized cell-to-cell similarity metric.Zhi-Jie CaoLin WeiShen LuDe-Chang YangGe GaoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Zhi-Jie Cao
Lin Wei
Shen Lu
De-Chang Yang
Ge Gao
Searching large-scale scRNA-seq databases via unbiased cell embedding with Cell BLAST
description Single-cell RNA-seq (scRNA-seq) is being widely used to resolve cellular heterogeneity. Here, the authors present a cell-querying method built on a neural network-based generative model and a customized cell-to-cell similarity metric.
format article
author Zhi-Jie Cao
Lin Wei
Shen Lu
De-Chang Yang
Ge Gao
author_facet Zhi-Jie Cao
Lin Wei
Shen Lu
De-Chang Yang
Ge Gao
author_sort Zhi-Jie Cao
title Searching large-scale scRNA-seq databases via unbiased cell embedding with Cell BLAST
title_short Searching large-scale scRNA-seq databases via unbiased cell embedding with Cell BLAST
title_full Searching large-scale scRNA-seq databases via unbiased cell embedding with Cell BLAST
title_fullStr Searching large-scale scRNA-seq databases via unbiased cell embedding with Cell BLAST
title_full_unstemmed Searching large-scale scRNA-seq databases via unbiased cell embedding with Cell BLAST
title_sort searching large-scale scrna-seq databases via unbiased cell embedding with cell blast
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/3e0cf5f83c044e5689b8ee6fcaa6bccd
work_keys_str_mv AT zhijiecao searchinglargescalescrnaseqdatabasesviaunbiasedcellembeddingwithcellblast
AT linwei searchinglargescalescrnaseqdatabasesviaunbiasedcellembeddingwithcellblast
AT shenlu searchinglargescalescrnaseqdatabasesviaunbiasedcellembeddingwithcellblast
AT dechangyang searchinglargescalescrnaseqdatabasesviaunbiasedcellembeddingwithcellblast
AT gegao searchinglargescalescrnaseqdatabasesviaunbiasedcellembeddingwithcellblast
_version_ 1718384285389422592

Documents similaires