Searching large-scale scRNA-seq databases via unbiased cell embedding with Cell BLAST

Single-cell RNA-seq (scRNA-seq) is being widely used to resolve cellular heterogeneity. Here, the authors present a cell-querying method built on a neural network-based generative model and a customized cell-to-cell similarity metric.

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Autores principales:	Zhi-Jie Cao, Lin Wei, Shen Lu, De-Chang Yang, Ge Gao
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3e0cf5f83c044e5689b8ee6fcaa6bccd
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:3e0cf5f83c044e5689b8ee6fcaa6bccd2021-12-02T16:15:09ZSearching large-scale scRNA-seq databases via unbiased cell embedding with Cell BLAST10.1038/s41467-020-17281-72041-1723https://doaj.org/article/3e0cf5f83c044e5689b8ee6fcaa6bccd2020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17281-7https://doaj.org/toc/2041-1723Single-cell RNA-seq (scRNA-seq) is being widely used to resolve cellular heterogeneity. Here, the authors present a cell-querying method built on a neural network-based generative model and a customized cell-to-cell similarity metric.Zhi-Jie CaoLin WeiShen LuDe-Chang YangGe GaoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Zhi-Jie Cao Lin Wei Shen Lu De-Chang Yang Ge Gao Searching large-scale scRNA-seq databases via unbiased cell embedding with Cell BLAST
description	Single-cell RNA-seq (scRNA-seq) is being widely used to resolve cellular heterogeneity. Here, the authors present a cell-querying method built on a neural network-based generative model and a customized cell-to-cell similarity metric.
format	article
author	Zhi-Jie Cao Lin Wei Shen Lu De-Chang Yang Ge Gao
author_facet	Zhi-Jie Cao Lin Wei Shen Lu De-Chang Yang Ge Gao
author_sort	Zhi-Jie Cao
title	Searching large-scale scRNA-seq databases via unbiased cell embedding with Cell BLAST
title_short	Searching large-scale scRNA-seq databases via unbiased cell embedding with Cell BLAST
title_full	Searching large-scale scRNA-seq databases via unbiased cell embedding with Cell BLAST
title_fullStr	Searching large-scale scRNA-seq databases via unbiased cell embedding with Cell BLAST
title_full_unstemmed	Searching large-scale scRNA-seq databases via unbiased cell embedding with Cell BLAST
title_sort	searching large-scale scrna-seq databases via unbiased cell embedding with cell blast
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/3e0cf5f83c044e5689b8ee6fcaa6bccd
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Searching large-scale scRNA-seq databases via unbiased cell embedding with Cell BLAST

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