FUCTIONAL OUTCOME OF ACUTE DISSEMINATED ENCEPHALOMYELITIS IN CHILDREN

Objective: To determine functional outcome of acute disseminated encephalomyelitis in children and factors affecting outcome at The Children’s Hospital, Lahore. Study Design: Cross-sectional observational study. Place and Duration of Study: Department of Pediatric Neurology, The Children’s Hospit...

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Autores principales:	Muhammad Zia Ur Rehman, Tipu Sultan, Shaila Ali
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2018
Materias:	acute disseminated encephalomyelitis consciousness encephalopathy Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/3e0dcdf50e66431c8ed639ebe798b252
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spelling	oai:doaj.org-article:3e0dcdf50e66431c8ed639ebe798b2522021-12-02T07:00:56ZFUCTIONAL OUTCOME OF ACUTE DISSEMINATED ENCEPHALOMYELITIS IN CHILDREN0030-96482411-8842https://doaj.org/article/3e0dcdf50e66431c8ed639ebe798b2522018-10-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/2313/2007https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To determine functional outcome of acute disseminated encephalomyelitis in children and factors affecting outcome at The Children’s Hospital, Lahore. Study Design: Cross-sectional observational study. Place and Duration of Study: Department of Pediatric Neurology, The Children’s Hospital and Institute of Child Health, Lahore from Nov 2014 to Oct 2015. Material and Methods: Fifteen patients with acute disseminated encephalomyelitis fulfilling the inclusion criteria were enrolled. Detailed history, examination, prior febrile illness and modified Rankin scale score for functional disability at presentation and discharge were recorded through study proforma. All patients underwent lumbar puncture and neuroimaging. Data were analysed in SPSS (v.20) and Chi-square test was applied to find p-value. Results: Out of 15 patients, there was male predominance (10 male 66.7%) with mean age 7.4 ± 2.5 years. Encephalopathy 100% (n=15) followed by fever, fits 73.3% (n=11) and motor deficit 60% (n=9) were common presentation. About 46.7% (n=7) cases had prior febrile illness. MRI brain had >5 lesions in 86.7% (n=13) with sub-cortical area 93.3% (n=14) periventricular area 86.7% (n=13). Functional outcome was good in 80% (modified Rankin scale of 2 or less at time of discharge). Consciousness level and disability score at presentation were statistically significant factors affecting the outcome (p-value 0.004 & 0.002 respectively). Conclusion: Acute disseminated encephalomyelitis in children had variable clinical presentation. It has good outcome with level of consciousness and disability score being significant factors affecting outcome.Muhammad Zia Ur RehmanTipu SultanShaila AliArmy Medical College Rawalpindiarticleacute disseminated encephalomyelitisconsciousnessencephalopathyMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 68, Iss 5, Pp 1306-1312 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	acute disseminated encephalomyelitis consciousness encephalopathy Medicine R Medicine (General) R5-920
spellingShingle	acute disseminated encephalomyelitis consciousness encephalopathy Medicine R Medicine (General) R5-920 Muhammad Zia Ur Rehman Tipu Sultan Shaila Ali FUCTIONAL OUTCOME OF ACUTE DISSEMINATED ENCEPHALOMYELITIS IN CHILDREN
description	Objective: To determine functional outcome of acute disseminated encephalomyelitis in children and factors affecting outcome at The Children’s Hospital, Lahore. Study Design: Cross-sectional observational study. Place and Duration of Study: Department of Pediatric Neurology, The Children’s Hospital and Institute of Child Health, Lahore from Nov 2014 to Oct 2015. Material and Methods: Fifteen patients with acute disseminated encephalomyelitis fulfilling the inclusion criteria were enrolled. Detailed history, examination, prior febrile illness and modified Rankin scale score for functional disability at presentation and discharge were recorded through study proforma. All patients underwent lumbar puncture and neuroimaging. Data were analysed in SPSS (v.20) and Chi-square test was applied to find p-value. Results: Out of 15 patients, there was male predominance (10 male 66.7%) with mean age 7.4 ± 2.5 years. Encephalopathy 100% (n=15) followed by fever, fits 73.3% (n=11) and motor deficit 60% (n=9) were common presentation. About 46.7% (n=7) cases had prior febrile illness. MRI brain had >5 lesions in 86.7% (n=13) with sub-cortical area 93.3% (n=14) periventricular area 86.7% (n=13). Functional outcome was good in 80% (modified Rankin scale of 2 or less at time of discharge). Consciousness level and disability score at presentation were statistically significant factors affecting the outcome (p-value 0.004 & 0.002 respectively). Conclusion: Acute disseminated encephalomyelitis in children had variable clinical presentation. It has good outcome with level of consciousness and disability score being significant factors affecting outcome.
format	article
author	Muhammad Zia Ur Rehman Tipu Sultan Shaila Ali
author_facet	Muhammad Zia Ur Rehman Tipu Sultan Shaila Ali
author_sort	Muhammad Zia Ur Rehman
title	FUCTIONAL OUTCOME OF ACUTE DISSEMINATED ENCEPHALOMYELITIS IN CHILDREN
title_short	FUCTIONAL OUTCOME OF ACUTE DISSEMINATED ENCEPHALOMYELITIS IN CHILDREN
title_full	FUCTIONAL OUTCOME OF ACUTE DISSEMINATED ENCEPHALOMYELITIS IN CHILDREN
title_fullStr	FUCTIONAL OUTCOME OF ACUTE DISSEMINATED ENCEPHALOMYELITIS IN CHILDREN
title_full_unstemmed	FUCTIONAL OUTCOME OF ACUTE DISSEMINATED ENCEPHALOMYELITIS IN CHILDREN
title_sort	fuctional outcome of acute disseminated encephalomyelitis in children
publisher	Army Medical College Rawalpindi
publishDate	2018
url	https://doaj.org/article/3e0dcdf50e66431c8ed639ebe798b252
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FUCTIONAL OUTCOME OF ACUTE DISSEMINATED ENCEPHALOMYELITIS IN CHILDREN

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