Anomalous origin of the right coronary artery with interarterial course: a mid-term follow-up of 28 cases

Abstract Anomalous origin of the right coronary artery from the opposite sinus (right-ACAOS) with interarterial course (IAC) has been associated with increased risk of sudden cardiac death (SCD). Widespread use of coronary computed tomography angiography (CCTA) has led to increased recognition of th...

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Autores principales:	Francisco Albuquerque, Pedro de Araújo Gonçalves, Hugo Marques, António Ferreira, Pedro Freitas, Pedro Lopes, Mariana Gonçalves, Hélder Dores, Nuno Cardim
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/3e19188030d842f98918194fc9864d0b
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spelling	oai:doaj.org-article:3e19188030d842f98918194fc9864d0b2021-12-02T15:14:28ZAnomalous origin of the right coronary artery with interarterial course: a mid-term follow-up of 28 cases10.1038/s41598-021-97917-w2045-2322https://doaj.org/article/3e19188030d842f98918194fc9864d0b2021-09-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-97917-whttps://doaj.org/toc/2045-2322Abstract Anomalous origin of the right coronary artery from the opposite sinus (right-ACAOS) with interarterial course (IAC) has been associated with increased risk of sudden cardiac death (SCD). Widespread use of coronary computed tomography angiography (CCTA) has led to increased recognition of this condition, even among healthy individuals. Our study sought to examine the prevalence, anatomical characteristics, and outcomes of right-ACAOS with IAC in patients undergoing CCTA for suspected coronary artery disease (CAD). We conducted a retrospective analysis of consecutive patients referred for CCTA at one tertiary hospital from January 2012 to December 2020. Patients exhibiting right-ACAOS with IAC were analyzed for cardiac symptoms and mid-term occurrence of first MACE (cardiac death, SCD, non-fatal myocardial infarction (MI) or revascularization of the anomalous vessel). CCTAs were reviewed for anatomical high-risk features and concomitant CAD. Among 10,928 patients referred for CCTA, 28 patients with right-ACAOS with IAC were identified. Mean age was 55 ± 17 years, 64% were male and 11 (39.3%) presented stable cardiac symptoms. Most patients had at least one high risk anatomical feature. During follow-up, there were no cardiac deaths or aborted SCD episodes and only 1 patient underwent surgical revascularization of the anomalous vessel. Right-ACAOS with IAC is an uncommon finding (prevalence of 0.26%). In a contemporary population of predominantly asymptomatic patients who survived this condition well into adulthood, most patients were managed conservatively with a low event rate. Additional studies are needed to support medical follow-up as the preferred option in this setting.Francisco AlbuquerquePedro de Araújo GonçalvesHugo MarquesAntónio FerreiraPedro FreitasPedro LopesMariana GonçalvesHélder DoresNuno CardimNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Francisco Albuquerque Pedro de Araújo Gonçalves Hugo Marques António Ferreira Pedro Freitas Pedro Lopes Mariana Gonçalves Hélder Dores Nuno Cardim Anomalous origin of the right coronary artery with interarterial course: a mid-term follow-up of 28 cases
description	Abstract Anomalous origin of the right coronary artery from the opposite sinus (right-ACAOS) with interarterial course (IAC) has been associated with increased risk of sudden cardiac death (SCD). Widespread use of coronary computed tomography angiography (CCTA) has led to increased recognition of this condition, even among healthy individuals. Our study sought to examine the prevalence, anatomical characteristics, and outcomes of right-ACAOS with IAC in patients undergoing CCTA for suspected coronary artery disease (CAD). We conducted a retrospective analysis of consecutive patients referred for CCTA at one tertiary hospital from January 2012 to December 2020. Patients exhibiting right-ACAOS with IAC were analyzed for cardiac symptoms and mid-term occurrence of first MACE (cardiac death, SCD, non-fatal myocardial infarction (MI) or revascularization of the anomalous vessel). CCTAs were reviewed for anatomical high-risk features and concomitant CAD. Among 10,928 patients referred for CCTA, 28 patients with right-ACAOS with IAC were identified. Mean age was 55 ± 17 years, 64% were male and 11 (39.3%) presented stable cardiac symptoms. Most patients had at least one high risk anatomical feature. During follow-up, there were no cardiac deaths or aborted SCD episodes and only 1 patient underwent surgical revascularization of the anomalous vessel. Right-ACAOS with IAC is an uncommon finding (prevalence of 0.26%). In a contemporary population of predominantly asymptomatic patients who survived this condition well into adulthood, most patients were managed conservatively with a low event rate. Additional studies are needed to support medical follow-up as the preferred option in this setting.
format	article
author	Francisco Albuquerque Pedro de Araújo Gonçalves Hugo Marques António Ferreira Pedro Freitas Pedro Lopes Mariana Gonçalves Hélder Dores Nuno Cardim
author_facet	Francisco Albuquerque Pedro de Araújo Gonçalves Hugo Marques António Ferreira Pedro Freitas Pedro Lopes Mariana Gonçalves Hélder Dores Nuno Cardim
author_sort	Francisco Albuquerque
title	Anomalous origin of the right coronary artery with interarterial course: a mid-term follow-up of 28 cases
title_short	Anomalous origin of the right coronary artery with interarterial course: a mid-term follow-up of 28 cases
title_full	Anomalous origin of the right coronary artery with interarterial course: a mid-term follow-up of 28 cases
title_fullStr	Anomalous origin of the right coronary artery with interarterial course: a mid-term follow-up of 28 cases
title_full_unstemmed	Anomalous origin of the right coronary artery with interarterial course: a mid-term follow-up of 28 cases
title_sort	anomalous origin of the right coronary artery with interarterial course: a mid-term follow-up of 28 cases
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/3e19188030d842f98918194fc9864d0b
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Anomalous origin of the right coronary artery with interarterial course: a mid-term follow-up of 28 cases

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