Eff ect of a single asenapine treatment on Fos expression in the brain catecholamine-synthesizing neurons: impact of a chronic mild stress preconditioning

Objective. Fos protein expression in catecholamine-synthesizing neurons of the substantia nigra (SN) pars compacta (SNC, A8), pars reticulata (SNR, A9), and pars lateralis (SNL), the ventral tegmental area (VTA, A10), the locus coeruleus (LC, A6) and subcoeruleus (sLC), the ventrolateral pons (PON-A...

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Autores principales:	Osacka J., Horvathova L., Majercikova Z., Kiss Alexander
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2017
Materias:	asenapine chronic mild stress preconditioning fos immunohistochemistry tyrosine hydroxylase immunohistochemistry rat Diseases of the endocrine glands. Clinical endocrinology RC648-665
Acceso en línea:	https://doaj.org/article/3e1da24499b64571b33458b3e9dd475e
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spelling	oai:doaj.org-article:3e1da24499b64571b33458b3e9dd475e2021-12-02T16:33:01ZEff ect of a single asenapine treatment on Fos expression in the brain catecholamine-synthesizing neurons: impact of a chronic mild stress preconditioning1336-032910.1515/enr-2017-0007https://doaj.org/article/3e1da24499b64571b33458b3e9dd475e2017-04-01T00:00:00Zhttps://doi.org/10.1515/enr-2017-0007https://doaj.org/toc/1336-0329Objective. Fos protein expression in catecholamine-synthesizing neurons of the substantia nigra (SN) pars compacta (SNC, A8), pars reticulata (SNR, A9), and pars lateralis (SNL), the ventral tegmental area (VTA, A10), the locus coeruleus (LC, A6) and subcoeruleus (sLC), the ventrolateral pons (PON-A5), the nucleus of the solitary tract (NTS-A2), the area postrema (AP), and the ventrolateral medulla (VLM-A1) was quantitatively evaluated aft er a single administration of asenapine (ASE) (designated for schizophrenia treatment) in male Wistar rats preconditioned with a chronic unpredictable variable mild stress (CMS) for 21 days. Th e aim of the present study was to reveal whether a single ASE treatment may 1) activate Fos expression in the brain areas selected; 2) activate tyrosine hydroxylase (TH)-synthesizing cells displaying Fos presence; and 3) be modulated by CMS preconditioning.Osacka J.Horvathova L.Majercikova Z.Kiss AlexanderSciendoarticleasenapinechronic mild stress preconditioningfos immunohistochemistrytyrosine hydroxylase immunohistochemistryratDiseases of the endocrine glands. Clinical endocrinologyRC648-665ENEndocrine Regulations, Vol 51, Iss 2, Pp 73-83 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	asenapine chronic mild stress preconditioning fos immunohistochemistry tyrosine hydroxylase immunohistochemistry rat Diseases of the endocrine glands. Clinical endocrinology RC648-665
spellingShingle	asenapine chronic mild stress preconditioning fos immunohistochemistry tyrosine hydroxylase immunohistochemistry rat Diseases of the endocrine glands. Clinical endocrinology RC648-665 Osacka J. Horvathova L. Majercikova Z. Kiss Alexander Eff ect of a single asenapine treatment on Fos expression in the brain catecholamine-synthesizing neurons: impact of a chronic mild stress preconditioning
description	Objective. Fos protein expression in catecholamine-synthesizing neurons of the substantia nigra (SN) pars compacta (SNC, A8), pars reticulata (SNR, A9), and pars lateralis (SNL), the ventral tegmental area (VTA, A10), the locus coeruleus (LC, A6) and subcoeruleus (sLC), the ventrolateral pons (PON-A5), the nucleus of the solitary tract (NTS-A2), the area postrema (AP), and the ventrolateral medulla (VLM-A1) was quantitatively evaluated aft er a single administration of asenapine (ASE) (designated for schizophrenia treatment) in male Wistar rats preconditioned with a chronic unpredictable variable mild stress (CMS) for 21 days. Th e aim of the present study was to reveal whether a single ASE treatment may 1) activate Fos expression in the brain areas selected; 2) activate tyrosine hydroxylase (TH)-synthesizing cells displaying Fos presence; and 3) be modulated by CMS preconditioning.
format	article
author	Osacka J. Horvathova L. Majercikova Z. Kiss Alexander
author_facet	Osacka J. Horvathova L. Majercikova Z. Kiss Alexander
author_sort	Osacka J.
title	Eff ect of a single asenapine treatment on Fos expression in the brain catecholamine-synthesizing neurons: impact of a chronic mild stress preconditioning
title_short	Eff ect of a single asenapine treatment on Fos expression in the brain catecholamine-synthesizing neurons: impact of a chronic mild stress preconditioning
title_full	Eff ect of a single asenapine treatment on Fos expression in the brain catecholamine-synthesizing neurons: impact of a chronic mild stress preconditioning
title_fullStr	Eff ect of a single asenapine treatment on Fos expression in the brain catecholamine-synthesizing neurons: impact of a chronic mild stress preconditioning
title_full_unstemmed	Eff ect of a single asenapine treatment on Fos expression in the brain catecholamine-synthesizing neurons: impact of a chronic mild stress preconditioning
title_sort	eff ect of a single asenapine treatment on fos expression in the brain catecholamine-synthesizing neurons: impact of a chronic mild stress preconditioning
publisher	Sciendo
publishDate	2017
url	https://doaj.org/article/3e1da24499b64571b33458b3e9dd475e
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Eff ect of a single asenapine treatment on Fos expression in the brain catecholamine-synthesizing neurons: impact of a chronic mild stress preconditioning

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