Membrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems
Laursen et al. investigates the role of membrane anchoring for the organization and efficiency of P450-driven plant metabolism. They report an original experimental design to monitor interactions between anchoring segments of membrane-bound enzymes at the single molecule level, using the cytochrome...
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Nature Portfolio
2021
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oai:doaj.org-article:3e1e47113b9c433fa180873c4a5ccde72021-12-02T19:13:48ZMembrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems10.1038/s42003-021-02604-12399-3642https://doaj.org/article/3e1e47113b9c433fa180873c4a5ccde72021-09-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02604-1https://doaj.org/toc/2399-3642Laursen et al. investigates the role of membrane anchoring for the organization and efficiency of P450-driven plant metabolism. They report an original experimental design to monitor interactions between anchoring segments of membrane-bound enzymes at the single molecule level, using the cytochrome P450 oxidoreductase (POR) transmembrane segment as a model, and propose that membrane anchoring has played a key role in the evolution of P450- based metabolic pathways in plants.Tomas LaursenHiu Yue Monatrice LamKasper Kildegaard SørensenPengfei TianCecilie Cetti HansenJay T. GrovesKnud Jørgen JensenSune M. ChristensenNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-9 (2021) |
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Biology (General) QH301-705.5 |
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Biology (General) QH301-705.5 Tomas Laursen Hiu Yue Monatrice Lam Kasper Kildegaard Sørensen Pengfei Tian Cecilie Cetti Hansen Jay T. Groves Knud Jørgen Jensen Sune M. Christensen Membrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems |
description |
Laursen et al. investigates the role of membrane anchoring for the organization and efficiency of P450-driven plant metabolism. They report an original experimental design to monitor interactions between anchoring segments of membrane-bound enzymes at the single molecule level, using the cytochrome P450 oxidoreductase (POR) transmembrane segment as a model, and propose that membrane anchoring has played a key role in the evolution of P450- based metabolic pathways in plants. |
format |
article |
author |
Tomas Laursen Hiu Yue Monatrice Lam Kasper Kildegaard Sørensen Pengfei Tian Cecilie Cetti Hansen Jay T. Groves Knud Jørgen Jensen Sune M. Christensen |
author_facet |
Tomas Laursen Hiu Yue Monatrice Lam Kasper Kildegaard Sørensen Pengfei Tian Cecilie Cetti Hansen Jay T. Groves Knud Jørgen Jensen Sune M. Christensen |
author_sort |
Tomas Laursen |
title |
Membrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems |
title_short |
Membrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems |
title_full |
Membrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems |
title_fullStr |
Membrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems |
title_full_unstemmed |
Membrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems |
title_sort |
membrane anchoring facilitates colocalization of enzymes in plant cytochrome p450 redox systems |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/3e1e47113b9c433fa180873c4a5ccde7 |
work_keys_str_mv |
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1718377015359307776 |