Membrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems

Laursen et al. investigates the role of membrane anchoring for the organization and efficiency of P450-driven plant metabolism. They report an original experimental design to monitor interactions between anchoring segments of membrane-bound enzymes at the single molecule level, using the cytochrome...

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Autores principales:	Tomas Laursen, Hiu Yue Monatrice Lam, Kasper Kildegaard Sørensen, Pengfei Tian, Cecilie Cetti Hansen, Jay T. Groves, Knud Jørgen Jensen, Sune M. Christensen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/3e1e47113b9c433fa180873c4a5ccde7
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spelling	oai:doaj.org-article:3e1e47113b9c433fa180873c4a5ccde72021-12-02T19:13:48ZMembrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems10.1038/s42003-021-02604-12399-3642https://doaj.org/article/3e1e47113b9c433fa180873c4a5ccde72021-09-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02604-1https://doaj.org/toc/2399-3642Laursen et al. investigates the role of membrane anchoring for the organization and efficiency of P450-driven plant metabolism. They report an original experimental design to monitor interactions between anchoring segments of membrane-bound enzymes at the single molecule level, using the cytochrome P450 oxidoreductase (POR) transmembrane segment as a model, and propose that membrane anchoring has played a key role in the evolution of P450- based metabolic pathways in plants.Tomas LaursenHiu Yue Monatrice LamKasper Kildegaard SørensenPengfei TianCecilie Cetti HansenJay T. GrovesKnud Jørgen JensenSune M. ChristensenNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Tomas Laursen Hiu Yue Monatrice Lam Kasper Kildegaard Sørensen Pengfei Tian Cecilie Cetti Hansen Jay T. Groves Knud Jørgen Jensen Sune M. Christensen Membrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems
description	Laursen et al. investigates the role of membrane anchoring for the organization and efficiency of P450-driven plant metabolism. They report an original experimental design to monitor interactions between anchoring segments of membrane-bound enzymes at the single molecule level, using the cytochrome P450 oxidoreductase (POR) transmembrane segment as a model, and propose that membrane anchoring has played a key role in the evolution of P450- based metabolic pathways in plants.
format	article
author	Tomas Laursen Hiu Yue Monatrice Lam Kasper Kildegaard Sørensen Pengfei Tian Cecilie Cetti Hansen Jay T. Groves Knud Jørgen Jensen Sune M. Christensen
author_facet	Tomas Laursen Hiu Yue Monatrice Lam Kasper Kildegaard Sørensen Pengfei Tian Cecilie Cetti Hansen Jay T. Groves Knud Jørgen Jensen Sune M. Christensen
author_sort	Tomas Laursen
title	Membrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems
title_short	Membrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems
title_full	Membrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems
title_fullStr	Membrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems
title_full_unstemmed	Membrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems
title_sort	membrane anchoring facilitates colocalization of enzymes in plant cytochrome p450 redox systems
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/3e1e47113b9c433fa180873c4a5ccde7
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_version_	1718377015359307776

Membrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems

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