Membrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems

Laursen et al. investigates the role of membrane anchoring for the organization and efficiency of P450-driven plant metabolism. They report an original experimental design to monitor interactions between anchoring segments of membrane-bound enzymes at the single molecule level, using the cytochrome...

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Autores principales: Tomas Laursen, Hiu Yue Monatrice Lam, Kasper Kildegaard Sørensen, Pengfei Tian, Cecilie Cetti Hansen, Jay T. Groves, Knud Jørgen Jensen, Sune M. Christensen
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/3e1e47113b9c433fa180873c4a5ccde7
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spelling oai:doaj.org-article:3e1e47113b9c433fa180873c4a5ccde72021-12-02T19:13:48ZMembrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems10.1038/s42003-021-02604-12399-3642https://doaj.org/article/3e1e47113b9c433fa180873c4a5ccde72021-09-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02604-1https://doaj.org/toc/2399-3642Laursen et al. investigates the role of membrane anchoring for the organization and efficiency of P450-driven plant metabolism. They report an original experimental design to monitor interactions between anchoring segments of membrane-bound enzymes at the single molecule level, using the cytochrome P450 oxidoreductase (POR) transmembrane segment as a model, and propose that membrane anchoring has played a key role in the evolution of P450- based metabolic pathways in plants.Tomas LaursenHiu Yue Monatrice LamKasper Kildegaard SørensenPengfei TianCecilie Cetti HansenJay T. GrovesKnud Jørgen JensenSune M. ChristensenNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-9 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Tomas Laursen
Hiu Yue Monatrice Lam
Kasper Kildegaard Sørensen
Pengfei Tian
Cecilie Cetti Hansen
Jay T. Groves
Knud Jørgen Jensen
Sune M. Christensen
Membrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems
description Laursen et al. investigates the role of membrane anchoring for the organization and efficiency of P450-driven plant metabolism. They report an original experimental design to monitor interactions between anchoring segments of membrane-bound enzymes at the single molecule level, using the cytochrome P450 oxidoreductase (POR) transmembrane segment as a model, and propose that membrane anchoring has played a key role in the evolution of P450- based metabolic pathways in plants.
format article
author Tomas Laursen
Hiu Yue Monatrice Lam
Kasper Kildegaard Sørensen
Pengfei Tian
Cecilie Cetti Hansen
Jay T. Groves
Knud Jørgen Jensen
Sune M. Christensen
author_facet Tomas Laursen
Hiu Yue Monatrice Lam
Kasper Kildegaard Sørensen
Pengfei Tian
Cecilie Cetti Hansen
Jay T. Groves
Knud Jørgen Jensen
Sune M. Christensen
author_sort Tomas Laursen
title Membrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems
title_short Membrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems
title_full Membrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems
title_fullStr Membrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems
title_full_unstemmed Membrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems
title_sort membrane anchoring facilitates colocalization of enzymes in plant cytochrome p450 redox systems
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/3e1e47113b9c433fa180873c4a5ccde7
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AT kasperkildegaardsørensen membraneanchoringfacilitatescolocalizationofenzymesinplantcytochromep450redoxsystems
AT pengfeitian membraneanchoringfacilitatescolocalizationofenzymesinplantcytochromep450redoxsystems
AT ceciliecettihansen membraneanchoringfacilitatescolocalizationofenzymesinplantcytochromep450redoxsystems
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AT knudjørgenjensen membraneanchoringfacilitatescolocalizationofenzymesinplantcytochromep450redoxsystems
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