A dynamic and adaptive network of cytosolic interactions governs protein export by the T3SS injectisome

Bacterial type III secretion systems (T3SS) play important roles in pathogenesis. Here, Diepoldet al. show the dynamic nature of complexes formed of essential T3SS components in live bacteria, and that extracellular calcium concentrations influence these cytosolic complexes likely via SctK/YscK.

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Detalles Bibliográficos
Autores principales: Andreas Diepold, Erdinc Sezgin, Miles Huseyin, Thomas Mortimer, Christian Eggeling, Judith P. Armitage
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/3e1f04d375c04aa3a541f55dd642d53b
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Sumario:Bacterial type III secretion systems (T3SS) play important roles in pathogenesis. Here, Diepoldet al. show the dynamic nature of complexes formed of essential T3SS components in live bacteria, and that extracellular calcium concentrations influence these cytosolic complexes likely via SctK/YscK.