A dynamic and adaptive network of cytosolic interactions governs protein export by the T3SS injectisome

Bacterial type III secretion systems (T3SS) play important roles in pathogenesis. Here, Diepoldet al. show the dynamic nature of complexes formed of essential T3SS components in live bacteria, and that extracellular calcium concentrations influence these cytosolic complexes likely via SctK/YscK.

Guardado en:
Detalles Bibliográficos
Autores principales: Andreas Diepold, Erdinc Sezgin, Miles Huseyin, Thomas Mortimer, Christian Eggeling, Judith P. Armitage
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Q
Acceso en línea:https://doaj.org/article/3e1f04d375c04aa3a541f55dd642d53b
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:3e1f04d375c04aa3a541f55dd642d53b
record_format dspace
spelling oai:doaj.org-article:3e1f04d375c04aa3a541f55dd642d53b2021-12-02T14:42:23ZA dynamic and adaptive network of cytosolic interactions governs protein export by the T3SS injectisome10.1038/ncomms159402041-1723https://doaj.org/article/3e1f04d375c04aa3a541f55dd642d53b2017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15940https://doaj.org/toc/2041-1723Bacterial type III secretion systems (T3SS) play important roles in pathogenesis. Here, Diepoldet al. show the dynamic nature of complexes formed of essential T3SS components in live bacteria, and that extracellular calcium concentrations influence these cytosolic complexes likely via SctK/YscK.Andreas DiepoldErdinc SezginMiles HuseyinThomas MortimerChristian EggelingJudith P. ArmitageNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Andreas Diepold
Erdinc Sezgin
Miles Huseyin
Thomas Mortimer
Christian Eggeling
Judith P. Armitage
A dynamic and adaptive network of cytosolic interactions governs protein export by the T3SS injectisome
description Bacterial type III secretion systems (T3SS) play important roles in pathogenesis. Here, Diepoldet al. show the dynamic nature of complexes formed of essential T3SS components in live bacteria, and that extracellular calcium concentrations influence these cytosolic complexes likely via SctK/YscK.
format article
author Andreas Diepold
Erdinc Sezgin
Miles Huseyin
Thomas Mortimer
Christian Eggeling
Judith P. Armitage
author_facet Andreas Diepold
Erdinc Sezgin
Miles Huseyin
Thomas Mortimer
Christian Eggeling
Judith P. Armitage
author_sort Andreas Diepold
title A dynamic and adaptive network of cytosolic interactions governs protein export by the T3SS injectisome
title_short A dynamic and adaptive network of cytosolic interactions governs protein export by the T3SS injectisome
title_full A dynamic and adaptive network of cytosolic interactions governs protein export by the T3SS injectisome
title_fullStr A dynamic and adaptive network of cytosolic interactions governs protein export by the T3SS injectisome
title_full_unstemmed A dynamic and adaptive network of cytosolic interactions governs protein export by the T3SS injectisome
title_sort dynamic and adaptive network of cytosolic interactions governs protein export by the t3ss injectisome
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/3e1f04d375c04aa3a541f55dd642d53b
work_keys_str_mv AT andreasdiepold adynamicandadaptivenetworkofcytosolicinteractionsgovernsproteinexportbythet3ssinjectisome
AT erdincsezgin adynamicandadaptivenetworkofcytosolicinteractionsgovernsproteinexportbythet3ssinjectisome
AT mileshuseyin adynamicandadaptivenetworkofcytosolicinteractionsgovernsproteinexportbythet3ssinjectisome
AT thomasmortimer adynamicandadaptivenetworkofcytosolicinteractionsgovernsproteinexportbythet3ssinjectisome
AT christianeggeling adynamicandadaptivenetworkofcytosolicinteractionsgovernsproteinexportbythet3ssinjectisome
AT judithparmitage adynamicandadaptivenetworkofcytosolicinteractionsgovernsproteinexportbythet3ssinjectisome
AT andreasdiepold dynamicandadaptivenetworkofcytosolicinteractionsgovernsproteinexportbythet3ssinjectisome
AT erdincsezgin dynamicandadaptivenetworkofcytosolicinteractionsgovernsproteinexportbythet3ssinjectisome
AT mileshuseyin dynamicandadaptivenetworkofcytosolicinteractionsgovernsproteinexportbythet3ssinjectisome
AT thomasmortimer dynamicandadaptivenetworkofcytosolicinteractionsgovernsproteinexportbythet3ssinjectisome
AT christianeggeling dynamicandadaptivenetworkofcytosolicinteractionsgovernsproteinexportbythet3ssinjectisome
AT judithparmitage dynamicandadaptivenetworkofcytosolicinteractionsgovernsproteinexportbythet3ssinjectisome
_version_ 1718389683970375680