TREATMENT OF ANXIODEPRESSIVE DISORDERS IN PATIENTS WITH CARDIOVASCULAR DISEASES

Sixty patients at the age of 43 to 79 years with anxiodepressive symptoms with comorbid cardiovascular disease have been examined after admission to psychotherapeutic department. Patients have been divided into two groups. The first group including 30 patients were treated by the tricyclic antidepre...

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Autores principales:	A. V. Khryashchev, N. K. Yagupova, A. V. Petrakova, T. V. Vorontsova
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2016
Materias:	tricyclic antidepressants anxiodepressive disorders cardiovascular disease Science Q
Acceso en línea:	https://doaj.org/article/3e224c45991c4922b902df572c3ce580
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spelling	oai:doaj.org-article:3e224c45991c4922b902df572c3ce5802021-11-23T06:14:36ZTREATMENT OF ANXIODEPRESSIVE DISORDERS IN PATIENTS WITH CARDIOVASCULAR DISEASES2541-94202587-959610.12737/23793https://doaj.org/article/3e224c45991c4922b902df572c3ce5802016-11-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/334https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Sixty patients at the age of 43 to 79 years with anxiodepressive symptoms with comorbid cardiovascular disease have been examined after admission to psychotherapeutic department. Patients have been divided into two groups. The first group including 30 patients were treated by the tricyclic antidepressant amitriptyline with the average daily dose of 34.4 ± 12.9 mg. The 30 patients from the second group were treated by antidepressants of the selective serotonin reuptake inhibitors group. The sociodemographic characteristics in both groups did not differ significantly; the severity of cardiovascular disease, additional somatic and other diseases were certainty lower in the first group than in the second (p < 0.05). Examination of the patients with the use of Hamilton Depression Rating Scale and Hamilton Anxiety Rating Scale (HDRS and HARS) was carried out three times: at admission, in 1 week and in 4 weeks. At the time of admission, anxiety and depression in the first group were more expressed (p < 0.05) than in the second due to frequent psychogeny. The treatment scheme included tranquilizers, neuroleptics, neurometabolic drugs, basic cardiotropic therapy and psychotherapy. After 4 weeks anxiodepressive symptoms were more than 50 % reduced in both groups: 61 % in the first group and 50.7 % in the second group by the HDRC scale; 65.9 % in the first group and 59.8 % in the second group by the HARS scale. It has been shown that the small doses of antidepressant including amitriptyline involved in the complex treatment scheme were efficient and did not cause cardiotoxic effect.A. V. KhryashchevN. K. YagupovaA. V. PetrakovaT. V. VorontsovaScientific Сentre for Family Health and Human Reproduction Problemsarticletricyclic antidepressantsanxiodepressive disorderscardiovascular diseaseScienceQRUActa Biomedica Scientifica, Vol 1, Iss 6, Pp 125-130 (2016)
institution	DOAJ
collection	DOAJ
language	RU
topic	tricyclic antidepressants anxiodepressive disorders cardiovascular disease Science Q
spellingShingle	tricyclic antidepressants anxiodepressive disorders cardiovascular disease Science Q A. V. Khryashchev N. K. Yagupova A. V. Petrakova T. V. Vorontsova TREATMENT OF ANXIODEPRESSIVE DISORDERS IN PATIENTS WITH CARDIOVASCULAR DISEASES
description	Sixty patients at the age of 43 to 79 years with anxiodepressive symptoms with comorbid cardiovascular disease have been examined after admission to psychotherapeutic department. Patients have been divided into two groups. The first group including 30 patients were treated by the tricyclic antidepressant amitriptyline with the average daily dose of 34.4 ± 12.9 mg. The 30 patients from the second group were treated by antidepressants of the selective serotonin reuptake inhibitors group. The sociodemographic characteristics in both groups did not differ significantly; the severity of cardiovascular disease, additional somatic and other diseases were certainty lower in the first group than in the second (p < 0.05). Examination of the patients with the use of Hamilton Depression Rating Scale and Hamilton Anxiety Rating Scale (HDRS and HARS) was carried out three times: at admission, in 1 week and in 4 weeks. At the time of admission, anxiety and depression in the first group were more expressed (p < 0.05) than in the second due to frequent psychogeny. The treatment scheme included tranquilizers, neuroleptics, neurometabolic drugs, basic cardiotropic therapy and psychotherapy. After 4 weeks anxiodepressive symptoms were more than 50 % reduced in both groups: 61 % in the first group and 50.7 % in the second group by the HDRC scale; 65.9 % in the first group and 59.8 % in the second group by the HARS scale. It has been shown that the small doses of antidepressant including amitriptyline involved in the complex treatment scheme were efficient and did not cause cardiotoxic effect.
format	article
author	A. V. Khryashchev N. K. Yagupova A. V. Petrakova T. V. Vorontsova
author_facet	A. V. Khryashchev N. K. Yagupova A. V. Petrakova T. V. Vorontsova
author_sort	A. V. Khryashchev
title	TREATMENT OF ANXIODEPRESSIVE DISORDERS IN PATIENTS WITH CARDIOVASCULAR DISEASES
title_short	TREATMENT OF ANXIODEPRESSIVE DISORDERS IN PATIENTS WITH CARDIOVASCULAR DISEASES
title_full	TREATMENT OF ANXIODEPRESSIVE DISORDERS IN PATIENTS WITH CARDIOVASCULAR DISEASES
title_fullStr	TREATMENT OF ANXIODEPRESSIVE DISORDERS IN PATIENTS WITH CARDIOVASCULAR DISEASES
title_full_unstemmed	TREATMENT OF ANXIODEPRESSIVE DISORDERS IN PATIENTS WITH CARDIOVASCULAR DISEASES
title_sort	treatment of anxiodepressive disorders in patients with cardiovascular diseases
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2016
url	https://doaj.org/article/3e224c45991c4922b902df572c3ce580
work_keys_str_mv	AT avkhryashchev treatmentofanxiodepressivedisordersinpatientswithcardiovasculardiseases AT nkyagupova treatmentofanxiodepressivedisordersinpatientswithcardiovasculardiseases AT avpetrakova treatmentofanxiodepressivedisordersinpatientswithcardiovasculardiseases AT tvvorontsova treatmentofanxiodepressivedisordersinpatientswithcardiovasculardiseases
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TREATMENT OF ANXIODEPRESSIVE DISORDERS IN PATIENTS WITH CARDIOVASCULAR DISEASES

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