Rhegmatogenous retinal detachments associated to Stickler syndrome in a tertiary eye care center in Saudi Arabia

Saeed T Alshahrani,1 Nicola G Ghazi,2 Saba Al-Rashaed2 1Ophthalmology Department, King Fahad Specialist Hospital, Dammam, 2Vitreoretinal Department, King Khaled Eye Specialist Hospital, Riyadh, Kingdom of Saudi Arabia Purpose: To investigate the clinical findings and outcomes of rhegmatogenous ret...

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Autores principales:	Alshahrani ST, Ghazi NG, Al-Rashaed S
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	rhegmatogenous retinal detachment Stickler syndrome retinopexy Gulf States Saudi Arabia. Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/3e2bfef0200d4e16bf6b6dbf9dfa5536
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spelling	oai:doaj.org-article:3e2bfef0200d4e16bf6b6dbf9dfa55362021-12-02T04:18:45ZRhegmatogenous retinal detachments associated to Stickler syndrome in a tertiary eye care center in Saudi Arabia1177-5483https://doaj.org/article/3e2bfef0200d4e16bf6b6dbf9dfa55362015-12-01T00:00:00Zhttps://www.dovepress.com/rhegmatogenous-retinal-detachments-associated-to-stickler-syndrome-in--peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Saeed T Alshahrani,1 Nicola G Ghazi,2 Saba Al-Rashaed2 1Ophthalmology Department, King Fahad Specialist Hospital, Dammam, 2Vitreoretinal Department, King Khaled Eye Specialist Hospital, Riyadh, Kingdom of Saudi Arabia Purpose: To investigate the clinical findings and outcomes of rhegmatogenous retinal detachment (RRD) in Stickler syndrome on affected and fellow eyes that underwent prophylactic retinopexy.Patients and methods: Chart review of 70 eyes (62 patients). Incidence of RRD, postoperative visual acuity, and risk factors were evaluated.Results: Twenty-two patients (35%) had RRD in the fellow eye, 37% of the eyes had cataract, 93% had macular detachment, 50% had proliferative vitreoretinopathy, and 41% had posterior vitreous detachment. Success rates were: 60% of patients after scleral buckling; 57.1% after pars plana vitrectomy; and 75% after combined scleral buckling and pars plana vitrectomy. Sixty-one (93.8%) of patients had successful surgery (including second surgery). Silicone oil tamponade was significantly associated with final anatomic outcome, with a protective odds ratio of 0.11 (P=0.027). Visual acuity improved in 54% of eyes and decreased in 5%. Statistically significant associations were present for eyes with final visual acuity ≥20/200, and total retinal detachment (P<0.001); preoperative cataract (P=0.023); and proliferative vitreoretinopathy (P<0.001). RRD developed in 16/44 eyes despite laser prophylaxis.Conclusion: Prophylactic retinopexy was not beneficial for Stickler syndrome patients. Success of primary surgery for RRD remains low. The primary surgery should be vitrectomy combined with scleral buckling and silicone oil tamponade. Keywords: Stickler syndrome, retinopexy, Gulf States, Saudi Arabia, ocular genetics, arthro-ophthalmopathy, collagen disorderAlshahrani STGhazi NGAl-Rashaed SDove Medical Pressarticlerhegmatogenous retinal detachmentStickler syndromeretinopexyGulf StatesSaudi Arabia.OphthalmologyRE1-994ENClinical Ophthalmology, Vol 2016, Iss Issue 1, Pp 1-6 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	rhegmatogenous retinal detachment Stickler syndrome retinopexy Gulf States Saudi Arabia. Ophthalmology RE1-994
spellingShingle	rhegmatogenous retinal detachment Stickler syndrome retinopexy Gulf States Saudi Arabia. Ophthalmology RE1-994 Alshahrani ST Ghazi NG Al-Rashaed S Rhegmatogenous retinal detachments associated to Stickler syndrome in a tertiary eye care center in Saudi Arabia
description	Saeed T Alshahrani,1 Nicola G Ghazi,2 Saba Al-Rashaed2 1Ophthalmology Department, King Fahad Specialist Hospital, Dammam, 2Vitreoretinal Department, King Khaled Eye Specialist Hospital, Riyadh, Kingdom of Saudi Arabia Purpose: To investigate the clinical findings and outcomes of rhegmatogenous retinal detachment (RRD) in Stickler syndrome on affected and fellow eyes that underwent prophylactic retinopexy.Patients and methods: Chart review of 70 eyes (62 patients). Incidence of RRD, postoperative visual acuity, and risk factors were evaluated.Results: Twenty-two patients (35%) had RRD in the fellow eye, 37% of the eyes had cataract, 93% had macular detachment, 50% had proliferative vitreoretinopathy, and 41% had posterior vitreous detachment. Success rates were: 60% of patients after scleral buckling; 57.1% after pars plana vitrectomy; and 75% after combined scleral buckling and pars plana vitrectomy. Sixty-one (93.8%) of patients had successful surgery (including second surgery). Silicone oil tamponade was significantly associated with final anatomic outcome, with a protective odds ratio of 0.11 (P=0.027). Visual acuity improved in 54% of eyes and decreased in 5%. Statistically significant associations were present for eyes with final visual acuity ≥20/200, and total retinal detachment (P<0.001); preoperative cataract (P=0.023); and proliferative vitreoretinopathy (P<0.001). RRD developed in 16/44 eyes despite laser prophylaxis.Conclusion: Prophylactic retinopexy was not beneficial for Stickler syndrome patients. Success of primary surgery for RRD remains low. The primary surgery should be vitrectomy combined with scleral buckling and silicone oil tamponade. Keywords: Stickler syndrome, retinopexy, Gulf States, Saudi Arabia, ocular genetics, arthro-ophthalmopathy, collagen disorder
format	article
author	Alshahrani ST Ghazi NG Al-Rashaed S
author_facet	Alshahrani ST Ghazi NG Al-Rashaed S
author_sort	Alshahrani ST
title	Rhegmatogenous retinal detachments associated to Stickler syndrome in a tertiary eye care center in Saudi Arabia
title_short	Rhegmatogenous retinal detachments associated to Stickler syndrome in a tertiary eye care center in Saudi Arabia
title_full	Rhegmatogenous retinal detachments associated to Stickler syndrome in a tertiary eye care center in Saudi Arabia
title_fullStr	Rhegmatogenous retinal detachments associated to Stickler syndrome in a tertiary eye care center in Saudi Arabia
title_full_unstemmed	Rhegmatogenous retinal detachments associated to Stickler syndrome in a tertiary eye care center in Saudi Arabia
title_sort	rhegmatogenous retinal detachments associated to stickler syndrome in a tertiary eye care center in saudi arabia
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/3e2bfef0200d4e16bf6b6dbf9dfa5536
work_keys_str_mv	AT alshahranist rhegmatogenousretinaldetachmentsassociatedtosticklersyndromeinatertiaryeyecarecenterinsaudiarabia AT ghazing rhegmatogenousretinaldetachmentsassociatedtosticklersyndromeinatertiaryeyecarecenterinsaudiarabia AT alrashaeds rhegmatogenousretinaldetachmentsassociatedtosticklersyndromeinatertiaryeyecarecenterinsaudiarabia
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Rhegmatogenous retinal detachments associated to Stickler syndrome in a tertiary eye care center in Saudi Arabia

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