Colonic perforation in a kidney recipient with Cytomegalovirus (CMV) colitis

Background and Objective: Gastrointestinal (GI) involvement is a cause of morbidity and mortality in kidney transplant recipients. Patients are at risk of GI infections during 1-6 months after transplantation. The major viral pathogen involving GI tract in transplanted patients is CMV. The incidence...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	F Oliaei, N Eshkevari, E Shafigh
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2005
Materias:	cytomegalovirus colitis colonic perforation transplantation Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/3e313801ab3c4aeb9cd99c6a2f8d2a0f
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:3e313801ab3c4aeb9cd99c6a2f8d2a0f
record_format	dspace
spelling	oai:doaj.org-article:3e313801ab3c4aeb9cd99c6a2f8d2a0f2021-11-10T09:14:25ZColonic perforation in a kidney recipient with Cytomegalovirus (CMV) colitis1561-41072251-7170https://doaj.org/article/3e313801ab3c4aeb9cd99c6a2f8d2a0f2005-01-01T00:00:00Zhttp://jbums.org/article-1-2661-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170Background and Objective: Gastrointestinal (GI) involvement is a cause of morbidity and mortality in kidney transplant recipients. Patients are at risk of GI infections during 1-6 months after transplantation. The major viral pathogen involving GI tract in transplanted patients is CMV. The incidence of active disease in seropositive patients is about 25%. There is a significant increase in mortality of kidney recipients suffering GI disease with CMV. Case: A 58-year-old man hospitalized with weakness and confusion three weeks after kidney transplantation. Gradually LLQ (Left lower quadrants) tenderness appeared. Abdominal X-ray showed subdiaphragmatic air. Sigmoidal perforation was revealed after abdominal laparotomy. CMV-PCR (Polymerase chain reaction) from blood was positive and CMV colitis was confirmed by colonic biopsy. Ganciclovir and broad-spectrum antibiotics were started but he died 5 days later because of sepsis. Conclusion: CMV disease may be fatal in kidney recipients. Despite severe disease, there may be just a few signs and symptoms. So, there must be a high index of suspicion in kidney recipients during first 6 months after transplantation.F OliaeiN EshkevariE ShafighBabol University of Medical Sciencesarticlecytomegaloviruscolitiscolonic perforationtransplantationMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 7, Iss 1, Pp 94-98 (2005)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	cytomegalovirus colitis colonic perforation transplantation Medicine R Medicine (General) R5-920
spellingShingle	cytomegalovirus colitis colonic perforation transplantation Medicine R Medicine (General) R5-920 F Oliaei N Eshkevari E Shafigh Colonic perforation in a kidney recipient with Cytomegalovirus (CMV) colitis
description	Background and Objective: Gastrointestinal (GI) involvement is a cause of morbidity and mortality in kidney transplant recipients. Patients are at risk of GI infections during 1-6 months after transplantation. The major viral pathogen involving GI tract in transplanted patients is CMV. The incidence of active disease in seropositive patients is about 25%. There is a significant increase in mortality of kidney recipients suffering GI disease with CMV. Case: A 58-year-old man hospitalized with weakness and confusion three weeks after kidney transplantation. Gradually LLQ (Left lower quadrants) tenderness appeared. Abdominal X-ray showed subdiaphragmatic air. Sigmoidal perforation was revealed after abdominal laparotomy. CMV-PCR (Polymerase chain reaction) from blood was positive and CMV colitis was confirmed by colonic biopsy. Ganciclovir and broad-spectrum antibiotics were started but he died 5 days later because of sepsis. Conclusion: CMV disease may be fatal in kidney recipients. Despite severe disease, there may be just a few signs and symptoms. So, there must be a high index of suspicion in kidney recipients during first 6 months after transplantation.
format	article
author	F Oliaei N Eshkevari E Shafigh
author_facet	F Oliaei N Eshkevari E Shafigh
author_sort	F Oliaei
title	Colonic perforation in a kidney recipient with Cytomegalovirus (CMV) colitis
title_short	Colonic perforation in a kidney recipient with Cytomegalovirus (CMV) colitis
title_full	Colonic perforation in a kidney recipient with Cytomegalovirus (CMV) colitis
title_fullStr	Colonic perforation in a kidney recipient with Cytomegalovirus (CMV) colitis
title_full_unstemmed	Colonic perforation in a kidney recipient with Cytomegalovirus (CMV) colitis
title_sort	colonic perforation in a kidney recipient with cytomegalovirus (cmv) colitis
publisher	Babol University of Medical Sciences
publishDate	2005
url	https://doaj.org/article/3e313801ab3c4aeb9cd99c6a2f8d2a0f
work_keys_str_mv	AT foliaei colonicperforationinakidneyrecipientwithcytomegaloviruscmvcolitis AT neshkevari colonicperforationinakidneyrecipientwithcytomegaloviruscmvcolitis AT eshafigh colonicperforationinakidneyrecipientwithcytomegaloviruscmvcolitis
_version_	1718440183926358016

Colonic perforation in a kidney recipient with Cytomegalovirus (CMV) colitis

Ejemplares similares