Integrated exome and RNA sequencing of dedifferentiated liposarcoma

Understanding the genomic features of dedifferentiated liposarcoma (DDLPS) is likely to uncover new options for management. Here, the authors reveal three prognostic groups, and highlight molecular markers associated with malignant transformation.

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Autores principales: Makoto Hirata, Naofumi Asano, Kotoe Katayama, Akihiko Yoshida, Yusuke Tsuda, Masaya Sekimizu, Sachiyo Mitani, Eisuke Kobayashi, Motokiyo Komiyama, Hiroyuki Fujimoto, Takahiro Goto, Yukihide Iwamoto, Norifumi Naka, Shintaro Iwata, Yoshihiro Nishida, Toru Hiruma, Hiroaki Hiraga, Hirotaka Kawano, Toru Motoi, Yoshinao Oda, Daisuke Matsubara, Masashi Fujita, Tatsuhiro Shibata, Hidewaki Nakagawa, Robert Nakayama, Tadashi Kondo, Seiya Imoto, Satoru Miyano, Akira Kawai, Rui Yamaguchi, Hitoshi Ichikawa, Koichi Matsuda
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/3e31fbc9656042eb9965085ae0110e72
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spelling oai:doaj.org-article:3e31fbc9656042eb9965085ae0110e722021-12-02T15:35:53ZIntegrated exome and RNA sequencing of dedifferentiated liposarcoma10.1038/s41467-019-13286-z2041-1723https://doaj.org/article/3e31fbc9656042eb9965085ae0110e722019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13286-zhttps://doaj.org/toc/2041-1723Understanding the genomic features of dedifferentiated liposarcoma (DDLPS) is likely to uncover new options for management. Here, the authors reveal three prognostic groups, and highlight molecular markers associated with malignant transformation.Makoto HirataNaofumi AsanoKotoe KatayamaAkihiko YoshidaYusuke TsudaMasaya SekimizuSachiyo MitaniEisuke KobayashiMotokiyo KomiyamaHiroyuki FujimotoTakahiro GotoYukihide IwamotoNorifumi NakaShintaro IwataYoshihiro NishidaToru HirumaHiroaki HiragaHirotaka KawanoToru MotoiYoshinao OdaDaisuke MatsubaraMasashi FujitaTatsuhiro ShibataHidewaki NakagawaRobert NakayamaTadashi KondoSeiya ImotoSatoru MiyanoAkira KawaiRui YamaguchiHitoshi IchikawaKoichi MatsudaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Makoto Hirata
Naofumi Asano
Kotoe Katayama
Akihiko Yoshida
Yusuke Tsuda
Masaya Sekimizu
Sachiyo Mitani
Eisuke Kobayashi
Motokiyo Komiyama
Hiroyuki Fujimoto
Takahiro Goto
Yukihide Iwamoto
Norifumi Naka
Shintaro Iwata
Yoshihiro Nishida
Toru Hiruma
Hiroaki Hiraga
Hirotaka Kawano
Toru Motoi
Yoshinao Oda
Daisuke Matsubara
Masashi Fujita
Tatsuhiro Shibata
Hidewaki Nakagawa
Robert Nakayama
Tadashi Kondo
Seiya Imoto
Satoru Miyano
Akira Kawai
Rui Yamaguchi
Hitoshi Ichikawa
Koichi Matsuda
Integrated exome and RNA sequencing of dedifferentiated liposarcoma
description Understanding the genomic features of dedifferentiated liposarcoma (DDLPS) is likely to uncover new options for management. Here, the authors reveal three prognostic groups, and highlight molecular markers associated with malignant transformation.
format article
author Makoto Hirata
Naofumi Asano
Kotoe Katayama
Akihiko Yoshida
Yusuke Tsuda
Masaya Sekimizu
Sachiyo Mitani
Eisuke Kobayashi
Motokiyo Komiyama
Hiroyuki Fujimoto
Takahiro Goto
Yukihide Iwamoto
Norifumi Naka
Shintaro Iwata
Yoshihiro Nishida
Toru Hiruma
Hiroaki Hiraga
Hirotaka Kawano
Toru Motoi
Yoshinao Oda
Daisuke Matsubara
Masashi Fujita
Tatsuhiro Shibata
Hidewaki Nakagawa
Robert Nakayama
Tadashi Kondo
Seiya Imoto
Satoru Miyano
Akira Kawai
Rui Yamaguchi
Hitoshi Ichikawa
Koichi Matsuda
author_facet Makoto Hirata
Naofumi Asano
Kotoe Katayama
Akihiko Yoshida
Yusuke Tsuda
Masaya Sekimizu
Sachiyo Mitani
Eisuke Kobayashi
Motokiyo Komiyama
Hiroyuki Fujimoto
Takahiro Goto
Yukihide Iwamoto
Norifumi Naka
Shintaro Iwata
Yoshihiro Nishida
Toru Hiruma
Hiroaki Hiraga
Hirotaka Kawano
Toru Motoi
Yoshinao Oda
Daisuke Matsubara
Masashi Fujita
Tatsuhiro Shibata
Hidewaki Nakagawa
Robert Nakayama
Tadashi Kondo
Seiya Imoto
Satoru Miyano
Akira Kawai
Rui Yamaguchi
Hitoshi Ichikawa
Koichi Matsuda
author_sort Makoto Hirata
title Integrated exome and RNA sequencing of dedifferentiated liposarcoma
title_short Integrated exome and RNA sequencing of dedifferentiated liposarcoma
title_full Integrated exome and RNA sequencing of dedifferentiated liposarcoma
title_fullStr Integrated exome and RNA sequencing of dedifferentiated liposarcoma
title_full_unstemmed Integrated exome and RNA sequencing of dedifferentiated liposarcoma
title_sort integrated exome and rna sequencing of dedifferentiated liposarcoma
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/3e31fbc9656042eb9965085ae0110e72
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