Multi-pronged neuromodulation intervention engages the residual motor circuitry to facilitate walking in a rat model of spinal cord injury

Deep brain stimulation and epidural electrical stimulation of the spinal cord enable locomotion in humans with spinal cord injury (SCI) but the potential synergy between both approaches is unclear. The authors show that a complex technological approach is required to enable volitional walking in rat...

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Autores principales:	Marco Bonizzato, Nicholas D. James, Galyna Pidpruzhnykova, Natalia Pavlova, Polina Shkorbatova, Laetitia Baud, Cristina Martinez-Gonzalez, Jordan W. Squair, Jack DiGiovanna, Quentin Barraud, Silvestro Micera, Gregoire Courtine
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3e33fdf15f7148f6ac0e70238e049c1c
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spelling	oai:doaj.org-article:3e33fdf15f7148f6ac0e70238e049c1c2021-12-02T11:44:50ZMulti-pronged neuromodulation intervention engages the residual motor circuitry to facilitate walking in a rat model of spinal cord injury10.1038/s41467-021-22137-92041-1723https://doaj.org/article/3e33fdf15f7148f6ac0e70238e049c1c2021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22137-9https://doaj.org/toc/2041-1723Deep brain stimulation and epidural electrical stimulation of the spinal cord enable locomotion in humans with spinal cord injury (SCI) but the potential synergy between both approaches is unclear. The authors show that a complex technological approach is required to enable volitional walking in rats with SCI.Marco BonizzatoNicholas D. JamesGalyna PidpruzhnykovaNatalia PavlovaPolina ShkorbatovaLaetitia BaudCristina Martinez-GonzalezJordan W. SquairJack DiGiovannaQuentin BarraudSilvestro MiceraGregoire CourtineNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Marco Bonizzato Nicholas D. James Galyna Pidpruzhnykova Natalia Pavlova Polina Shkorbatova Laetitia Baud Cristina Martinez-Gonzalez Jordan W. Squair Jack DiGiovanna Quentin Barraud Silvestro Micera Gregoire Courtine Multi-pronged neuromodulation intervention engages the residual motor circuitry to facilitate walking in a rat model of spinal cord injury
description	Deep brain stimulation and epidural electrical stimulation of the spinal cord enable locomotion in humans with spinal cord injury (SCI) but the potential synergy between both approaches is unclear. The authors show that a complex technological approach is required to enable volitional walking in rats with SCI.
format	article
author	Marco Bonizzato Nicholas D. James Galyna Pidpruzhnykova Natalia Pavlova Polina Shkorbatova Laetitia Baud Cristina Martinez-Gonzalez Jordan W. Squair Jack DiGiovanna Quentin Barraud Silvestro Micera Gregoire Courtine
author_facet	Marco Bonizzato Nicholas D. James Galyna Pidpruzhnykova Natalia Pavlova Polina Shkorbatova Laetitia Baud Cristina Martinez-Gonzalez Jordan W. Squair Jack DiGiovanna Quentin Barraud Silvestro Micera Gregoire Courtine
author_sort	Marco Bonizzato
title	Multi-pronged neuromodulation intervention engages the residual motor circuitry to facilitate walking in a rat model of spinal cord injury
title_short	Multi-pronged neuromodulation intervention engages the residual motor circuitry to facilitate walking in a rat model of spinal cord injury
title_full	Multi-pronged neuromodulation intervention engages the residual motor circuitry to facilitate walking in a rat model of spinal cord injury
title_fullStr	Multi-pronged neuromodulation intervention engages the residual motor circuitry to facilitate walking in a rat model of spinal cord injury
title_full_unstemmed	Multi-pronged neuromodulation intervention engages the residual motor circuitry to facilitate walking in a rat model of spinal cord injury
title_sort	multi-pronged neuromodulation intervention engages the residual motor circuitry to facilitate walking in a rat model of spinal cord injury
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/3e33fdf15f7148f6ac0e70238e049c1c
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Multi-pronged neuromodulation intervention engages the residual motor circuitry to facilitate walking in a rat model of spinal cord injury

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