HIF1α is required for NK cell metabolic adaptation during virus infection
Natural killer (NK) cells are essential for early protection against virus infection and must metabolically adapt to the energy demands of activation. Here, we found upregulation of the metabolic adaptor hypoxia-inducible factor-1α (HIF1α) is a feature of mouse NK cells during murine cytomegalovirus...
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Autores principales: | Francisco Victorino, Tarin M Bigley, Eugene Park, Cong-Hui Yao, Jeanne Benoit, Li-Ping Yang, Sytse J Piersma, Elvin J Lauron, Rebecca M Davidson, Gary J Patti, Wayne M Yokoyama |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
eLife Sciences Publications Ltd
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/3e3a62a1b135404db887eff1f946aea3 |
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