Incidence of Nasal Polyps Recurrence Rate in Patients with Eosinophilic Esophagitis after Endoscopic Endonasal Surgery

Background: Nasal polys [NPs] are frequently encountered inotorhinolaryngology practice. It had been proposed to share etiological origin with eosinophilic esophagitis [EOE]. However, there is not yet adequate estimations of this association and incidence of NPs recurrence after endonasal surgery in...

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Autores principales:	Nabil Abdelghany Sarhan, Mohamed Abdelkawi Fathallah, Ashraf Abdalla Wahba, Ahmed Mohamed Rabie, Sherief Abdelmohsen Mousa, Ahmed Alboraey Kabeel
Formato:	article
Lenguaje:	EN
Publicado:	Al-Azhar University, Faculty of Medicine (Damietta) 2020
Materias:	nasal polyps eosinophilic esophagitis allergic rhinitis eosinophilia sinonasal outcome test Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/3e46ca3ce20e40da852b8138b7791385
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spelling	oai:doaj.org-article:3e46ca3ce20e40da852b8138b77913852021-12-02T14:02:00ZIncidence of Nasal Polyps Recurrence Rate in Patients with Eosinophilic Esophagitis after Endoscopic Endonasal Surgery2636-41742682-378010.21608/ijma.2020.31129.1128https://doaj.org/article/3e46ca3ce20e40da852b8138b77913852020-10-01T00:00:00Zhttps://ijma.journals.ekb.eg/article_104654_517c4e2e6ebb0a53e1196e45e42d672e.pdfhttps://doaj.org/toc/2636-4174https://doaj.org/toc/2682-3780Background: Nasal polys [NPs] are frequently encountered inotorhinolaryngology practice. It had been proposed to share etiological origin with eosinophilic esophagitis [EOE]. However, there is not yet adequate estimations of this association and incidence of NPs recurrence after endonasal surgery in patients with EOE. Aim of the work: To evaluate incidence of recurrence of NPs after endoscopic endonasal surgery for patients with EOE. Patients and Methods: 150 patients were included and divided into three groups: the control [CG] [50 patients indicated for gastroscopy]. The nasal polyp’s subgroups consisted of 100 patients and further subdivided into two groups according to result of nasal biopsy into two subgroups, eosinophilic nasal polyps [ENP] group IIA; non-eosinophilic nasal polyps [NENP] group IIB. In NPs subgroups, sinonasal outcome test [SNOT22] had been performed to measure the health status and quality of life in patients with NPs through questions relating to their symptoms. The recurrence of nasal polyps were investigated after endoscopic sinus surgery and during follow up and outcome had been compared between groups. Results: 22% suffered polyp recurrence after surgery during the follow-up period. Patients with EOE had a significantly higher recurrence rate of nasal polyps [100%] in comparison to 16.4% in EOE patients. These results indicate that, mucosal eosinophilia is a determinant factor in the recurrence of nasal polyps. Hence in patients with EOE [had mucosal eosinophilia] who underwent endonasal surgery, the recurrence of nasal polyps should be highly expected. Conclusion: Mucosal eosinophilia in patients with EOE, and ENP are a more important prognostic factor in recurrence of nasal polyps.Nabil Abdelghany SarhanMohamed Abdelkawi FathallahAshraf Abdalla WahbaAhmed Mohamed RabieSherief Abdelmohsen MousaAhmed Alboraey KabeelAl-Azhar University, Faculty of Medicine (Damietta)articlenasal polypseosinophilic esophagitisallergic rhinitiseosinophiliasinonasal outcome testMedicine (General)R5-920ENInternational Journal of Medical Arts, Vol 2, Iss 4, Pp 741-748 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	nasal polyps eosinophilic esophagitis allergic rhinitis eosinophilia sinonasal outcome test Medicine (General) R5-920
spellingShingle	nasal polyps eosinophilic esophagitis allergic rhinitis eosinophilia sinonasal outcome test Medicine (General) R5-920 Nabil Abdelghany Sarhan Mohamed Abdelkawi Fathallah Ashraf Abdalla Wahba Ahmed Mohamed Rabie Sherief Abdelmohsen Mousa Ahmed Alboraey Kabeel Incidence of Nasal Polyps Recurrence Rate in Patients with Eosinophilic Esophagitis after Endoscopic Endonasal Surgery
description	Background: Nasal polys [NPs] are frequently encountered inotorhinolaryngology practice. It had been proposed to share etiological origin with eosinophilic esophagitis [EOE]. However, there is not yet adequate estimations of this association and incidence of NPs recurrence after endonasal surgery in patients with EOE. Aim of the work: To evaluate incidence of recurrence of NPs after endoscopic endonasal surgery for patients with EOE. Patients and Methods: 150 patients were included and divided into three groups: the control [CG] [50 patients indicated for gastroscopy]. The nasal polyp’s subgroups consisted of 100 patients and further subdivided into two groups according to result of nasal biopsy into two subgroups, eosinophilic nasal polyps [ENP] group IIA; non-eosinophilic nasal polyps [NENP] group IIB. In NPs subgroups, sinonasal outcome test [SNOT22] had been performed to measure the health status and quality of life in patients with NPs through questions relating to their symptoms. The recurrence of nasal polyps were investigated after endoscopic sinus surgery and during follow up and outcome had been compared between groups. Results: 22% suffered polyp recurrence after surgery during the follow-up period. Patients with EOE had a significantly higher recurrence rate of nasal polyps [100%] in comparison to 16.4% in EOE patients. These results indicate that, mucosal eosinophilia is a determinant factor in the recurrence of nasal polyps. Hence in patients with EOE [had mucosal eosinophilia] who underwent endonasal surgery, the recurrence of nasal polyps should be highly expected. Conclusion: Mucosal eosinophilia in patients with EOE, and ENP are a more important prognostic factor in recurrence of nasal polyps.
format	article
author	Nabil Abdelghany Sarhan Mohamed Abdelkawi Fathallah Ashraf Abdalla Wahba Ahmed Mohamed Rabie Sherief Abdelmohsen Mousa Ahmed Alboraey Kabeel
author_facet	Nabil Abdelghany Sarhan Mohamed Abdelkawi Fathallah Ashraf Abdalla Wahba Ahmed Mohamed Rabie Sherief Abdelmohsen Mousa Ahmed Alboraey Kabeel
author_sort	Nabil Abdelghany Sarhan
title	Incidence of Nasal Polyps Recurrence Rate in Patients with Eosinophilic Esophagitis after Endoscopic Endonasal Surgery
title_short	Incidence of Nasal Polyps Recurrence Rate in Patients with Eosinophilic Esophagitis after Endoscopic Endonasal Surgery
title_full	Incidence of Nasal Polyps Recurrence Rate in Patients with Eosinophilic Esophagitis after Endoscopic Endonasal Surgery
title_fullStr	Incidence of Nasal Polyps Recurrence Rate in Patients with Eosinophilic Esophagitis after Endoscopic Endonasal Surgery
title_full_unstemmed	Incidence of Nasal Polyps Recurrence Rate in Patients with Eosinophilic Esophagitis after Endoscopic Endonasal Surgery
title_sort	incidence of nasal polyps recurrence rate in patients with eosinophilic esophagitis after endoscopic endonasal surgery
publisher	Al-Azhar University, Faculty of Medicine (Damietta)
publishDate	2020
url	https://doaj.org/article/3e46ca3ce20e40da852b8138b7791385
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Incidence of Nasal Polyps Recurrence Rate in Patients with Eosinophilic Esophagitis after Endoscopic Endonasal Surgery

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