FoxO1 in dopaminergic neurons regulates energy homeostasis and targets tyrosine hydroxylase

Dopaminergic neurons are important for regulating energy homeostasis. Here, the authors show the transcription factor FoxO1 negatively regulates tyrosine hydroxylase expression in midbrain dopaminergic neurons, and plays an important role in regulation of glucose homeostasis, energy expenditure, and...

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Autores principales:	Khanh V. Doan, Ann W. Kinyua, Dong Joo Yang, Chang Mann Ko, Sang Hyun Moh, Ko Eun Shong, Hail Kim, Sang-Kyu Park, Dong-Hoon Kim, Inki Kim, Ji-Hye Paik, Ronald A. DePinho, Seul Gi Yoon, Il Yong Kim, Je Kyung Seong, Yun-Hee Choi, Ki Woo Kim
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3e52e79bfcb5442bbccc4038ce959381
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spelling	oai:doaj.org-article:3e52e79bfcb5442bbccc4038ce9593812021-12-02T16:49:58ZFoxO1 in dopaminergic neurons regulates energy homeostasis and targets tyrosine hydroxylase10.1038/ncomms127332041-1723https://doaj.org/article/3e52e79bfcb5442bbccc4038ce9593812016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12733https://doaj.org/toc/2041-1723Dopaminergic neurons are important for regulating energy homeostasis. Here, the authors show the transcription factor FoxO1 negatively regulates tyrosine hydroxylase expression in midbrain dopaminergic neurons, and plays an important role in regulation of glucose homeostasis, energy expenditure, and resistance to diet-induced obesity.Khanh V. DoanAnn W. KinyuaDong Joo YangChang Mann KoSang Hyun MohKo Eun ShongHail KimSang-Kyu ParkDong-Hoon KimInki KimJi-Hye PaikRonald A. DePinhoSeul Gi YoonIl Yong KimJe Kyung SeongYun-Hee ChoiKi Woo KimNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Khanh V. Doan Ann W. Kinyua Dong Joo Yang Chang Mann Ko Sang Hyun Moh Ko Eun Shong Hail Kim Sang-Kyu Park Dong-Hoon Kim Inki Kim Ji-Hye Paik Ronald A. DePinho Seul Gi Yoon Il Yong Kim Je Kyung Seong Yun-Hee Choi Ki Woo Kim FoxO1 in dopaminergic neurons regulates energy homeostasis and targets tyrosine hydroxylase
description	Dopaminergic neurons are important for regulating energy homeostasis. Here, the authors show the transcription factor FoxO1 negatively regulates tyrosine hydroxylase expression in midbrain dopaminergic neurons, and plays an important role in regulation of glucose homeostasis, energy expenditure, and resistance to diet-induced obesity.
format	article
author	Khanh V. Doan Ann W. Kinyua Dong Joo Yang Chang Mann Ko Sang Hyun Moh Ko Eun Shong Hail Kim Sang-Kyu Park Dong-Hoon Kim Inki Kim Ji-Hye Paik Ronald A. DePinho Seul Gi Yoon Il Yong Kim Je Kyung Seong Yun-Hee Choi Ki Woo Kim
author_facet	Khanh V. Doan Ann W. Kinyua Dong Joo Yang Chang Mann Ko Sang Hyun Moh Ko Eun Shong Hail Kim Sang-Kyu Park Dong-Hoon Kim Inki Kim Ji-Hye Paik Ronald A. DePinho Seul Gi Yoon Il Yong Kim Je Kyung Seong Yun-Hee Choi Ki Woo Kim
author_sort	Khanh V. Doan
title	FoxO1 in dopaminergic neurons regulates energy homeostasis and targets tyrosine hydroxylase
title_short	FoxO1 in dopaminergic neurons regulates energy homeostasis and targets tyrosine hydroxylase
title_full	FoxO1 in dopaminergic neurons regulates energy homeostasis and targets tyrosine hydroxylase
title_fullStr	FoxO1 in dopaminergic neurons regulates energy homeostasis and targets tyrosine hydroxylase
title_full_unstemmed	FoxO1 in dopaminergic neurons regulates energy homeostasis and targets tyrosine hydroxylase
title_sort	foxo1 in dopaminergic neurons regulates energy homeostasis and targets tyrosine hydroxylase
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/3e52e79bfcb5442bbccc4038ce959381
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FoxO1 in dopaminergic neurons regulates energy homeostasis and targets tyrosine hydroxylase

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