TRPV1 enhances the afferent response to P2X receptor activation in the mouse urinary bladder

TRPV1 enhances the afferent response to P2X receptor activation in the mouse urinary bladder

Abstract Both TRPV1 and P2X receptors present on bladder sensory nerve fibres have been implicated in mechanosensation during bladder filling. The aim of this study was to determine possible interactions between these receptors in modulating afferent nerve activity. In wildtype (TRPV1+/+) and TRPV1...

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Autores principales: Luke Grundy, Donna M. Daly, Christopher Chapple, David Grundy, Russ Chess-Williams
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/3e57c35388114772b91916e68ebcfb95
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