Two factor-based reprogramming of rodent and human fibroblasts into Schwann cells
Schwann cells (SCs) myelinate peripheral nerve axons and offer opportunities for the treatment of injuries and demyelinating diseases but reliable and renewable sources of these cells are hard to come by. Here the authors reprogram rat, mouse and human fibroblasts into Schwann cells using two transc...
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Nature Portfolio
2017
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oai:doaj.org-article:3e5822abc9d6496093cbde7fb62360242021-12-02T14:41:00ZTwo factor-based reprogramming of rodent and human fibroblasts into Schwann cells10.1038/ncomms140882041-1723https://doaj.org/article/3e5822abc9d6496093cbde7fb62360242017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14088https://doaj.org/toc/2041-1723Schwann cells (SCs) myelinate peripheral nerve axons and offer opportunities for the treatment of injuries and demyelinating diseases but reliable and renewable sources of these cells are hard to come by. Here the authors reprogram rat, mouse and human fibroblasts into Schwann cells using two transcription factors.Pietro Giuseppe MazzaraLuca MassiminoMarta PellegattaGiulia RonchiAlessandra RiccaAngelo IannielliSerena Gea GiannelliMarco CursiCinzia CancellieriAlessandro SessaUbaldo Del CarroAngelo QuattriniStefano GeunaAngela GrittiCarla TaveggiaVania BroccoliNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017) |
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Science Q Pietro Giuseppe Mazzara Luca Massimino Marta Pellegatta Giulia Ronchi Alessandra Ricca Angelo Iannielli Serena Gea Giannelli Marco Cursi Cinzia Cancellieri Alessandro Sessa Ubaldo Del Carro Angelo Quattrini Stefano Geuna Angela Gritti Carla Taveggia Vania Broccoli Two factor-based reprogramming of rodent and human fibroblasts into Schwann cells |
description |
Schwann cells (SCs) myelinate peripheral nerve axons and offer opportunities for the treatment of injuries and demyelinating diseases but reliable and renewable sources of these cells are hard to come by. Here the authors reprogram rat, mouse and human fibroblasts into Schwann cells using two transcription factors. |
format |
article |
author |
Pietro Giuseppe Mazzara Luca Massimino Marta Pellegatta Giulia Ronchi Alessandra Ricca Angelo Iannielli Serena Gea Giannelli Marco Cursi Cinzia Cancellieri Alessandro Sessa Ubaldo Del Carro Angelo Quattrini Stefano Geuna Angela Gritti Carla Taveggia Vania Broccoli |
author_facet |
Pietro Giuseppe Mazzara Luca Massimino Marta Pellegatta Giulia Ronchi Alessandra Ricca Angelo Iannielli Serena Gea Giannelli Marco Cursi Cinzia Cancellieri Alessandro Sessa Ubaldo Del Carro Angelo Quattrini Stefano Geuna Angela Gritti Carla Taveggia Vania Broccoli |
author_sort |
Pietro Giuseppe Mazzara |
title |
Two factor-based reprogramming of rodent and human fibroblasts into Schwann cells |
title_short |
Two factor-based reprogramming of rodent and human fibroblasts into Schwann cells |
title_full |
Two factor-based reprogramming of rodent and human fibroblasts into Schwann cells |
title_fullStr |
Two factor-based reprogramming of rodent and human fibroblasts into Schwann cells |
title_full_unstemmed |
Two factor-based reprogramming of rodent and human fibroblasts into Schwann cells |
title_sort |
two factor-based reprogramming of rodent and human fibroblasts into schwann cells |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/3e5822abc9d6496093cbde7fb6236024 |
work_keys_str_mv |
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1718390046733631488 |