Two factor-based reprogramming of rodent and human fibroblasts into Schwann cells

Schwann cells (SCs) myelinate peripheral nerve axons and offer opportunities for the treatment of injuries and demyelinating diseases but reliable and renewable sources of these cells are hard to come by. Here the authors reprogram rat, mouse and human fibroblasts into Schwann cells using two transc...

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Autores principales: Pietro Giuseppe Mazzara, Luca Massimino, Marta Pellegatta, Giulia Ronchi, Alessandra Ricca, Angelo Iannielli, Serena Gea Giannelli, Marco Cursi, Cinzia Cancellieri, Alessandro Sessa, Ubaldo Del Carro, Angelo Quattrini, Stefano Geuna, Angela Gritti, Carla Taveggia, Vania Broccoli
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/3e5822abc9d6496093cbde7fb6236024
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spelling oai:doaj.org-article:3e5822abc9d6496093cbde7fb62360242021-12-02T14:41:00ZTwo factor-based reprogramming of rodent and human fibroblasts into Schwann cells10.1038/ncomms140882041-1723https://doaj.org/article/3e5822abc9d6496093cbde7fb62360242017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14088https://doaj.org/toc/2041-1723Schwann cells (SCs) myelinate peripheral nerve axons and offer opportunities for the treatment of injuries and demyelinating diseases but reliable and renewable sources of these cells are hard to come by. Here the authors reprogram rat, mouse and human fibroblasts into Schwann cells using two transcription factors.Pietro Giuseppe MazzaraLuca MassiminoMarta PellegattaGiulia RonchiAlessandra RiccaAngelo IannielliSerena Gea GiannelliMarco CursiCinzia CancellieriAlessandro SessaUbaldo Del CarroAngelo QuattriniStefano GeunaAngela GrittiCarla TaveggiaVania BroccoliNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Pietro Giuseppe Mazzara
Luca Massimino
Marta Pellegatta
Giulia Ronchi
Alessandra Ricca
Angelo Iannielli
Serena Gea Giannelli
Marco Cursi
Cinzia Cancellieri
Alessandro Sessa
Ubaldo Del Carro
Angelo Quattrini
Stefano Geuna
Angela Gritti
Carla Taveggia
Vania Broccoli
Two factor-based reprogramming of rodent and human fibroblasts into Schwann cells
description Schwann cells (SCs) myelinate peripheral nerve axons and offer opportunities for the treatment of injuries and demyelinating diseases but reliable and renewable sources of these cells are hard to come by. Here the authors reprogram rat, mouse and human fibroblasts into Schwann cells using two transcription factors.
format article
author Pietro Giuseppe Mazzara
Luca Massimino
Marta Pellegatta
Giulia Ronchi
Alessandra Ricca
Angelo Iannielli
Serena Gea Giannelli
Marco Cursi
Cinzia Cancellieri
Alessandro Sessa
Ubaldo Del Carro
Angelo Quattrini
Stefano Geuna
Angela Gritti
Carla Taveggia
Vania Broccoli
author_facet Pietro Giuseppe Mazzara
Luca Massimino
Marta Pellegatta
Giulia Ronchi
Alessandra Ricca
Angelo Iannielli
Serena Gea Giannelli
Marco Cursi
Cinzia Cancellieri
Alessandro Sessa
Ubaldo Del Carro
Angelo Quattrini
Stefano Geuna
Angela Gritti
Carla Taveggia
Vania Broccoli
author_sort Pietro Giuseppe Mazzara
title Two factor-based reprogramming of rodent and human fibroblasts into Schwann cells
title_short Two factor-based reprogramming of rodent and human fibroblasts into Schwann cells
title_full Two factor-based reprogramming of rodent and human fibroblasts into Schwann cells
title_fullStr Two factor-based reprogramming of rodent and human fibroblasts into Schwann cells
title_full_unstemmed Two factor-based reprogramming of rodent and human fibroblasts into Schwann cells
title_sort two factor-based reprogramming of rodent and human fibroblasts into schwann cells
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/3e5822abc9d6496093cbde7fb6236024
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