Clinical Impact of Nurses-Physicians Collaboration Intervention on the Treatment of Immune Recurrent Spontaneous Abortion with Low-Molecular-Weight Heparin

Anticoagulation is currently the preferred and effective treatment for patients with recurrent spontaneous abortion (RSA), but, due to the prevalence of mood disorders in RSA patients and the high number of adverse effects associated with long-term medication, effective care measures are often requi...

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Autores principales:	Miaocheng Chen, Xi Wang, Peiru Deng
Formato:	article
Lenguaje:	EN
Publicado:	Hindawi Limited 2021
Materias:	Other systems of medicine RZ201-999
Acceso en línea:	https://doaj.org/article/3e5e92657ae3489c8b6ace2f1a720ed4
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spelling	oai:doaj.org-article:3e5e92657ae3489c8b6ace2f1a720ed42021-11-08T02:36:26ZClinical Impact of Nurses-Physicians Collaboration Intervention on the Treatment of Immune Recurrent Spontaneous Abortion with Low-Molecular-Weight Heparin1741-428810.1155/2021/9290720https://doaj.org/article/3e5e92657ae3489c8b6ace2f1a720ed42021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/9290720https://doaj.org/toc/1741-4288Anticoagulation is currently the preferred and effective treatment for patients with recurrent spontaneous abortion (RSA), but, due to the prevalence of mood disorders in RSA patients and the high number of adverse effects associated with long-term medication, effective care measures are often required. In this study, 94 patients with immune-type RSA who were admitted to our hospital from January 2018 to June 2019 were selected and randomly divided into a control group and a study group of 47 patients each; both groups received low-molecular-weight heparin treatment after admission, and the control group received conventional nursing interventions during treatment, while the patients in the study group received integrated medical and nursing care interventions. Pregnancy outcomes, pre- and postintervention scores on the Self-Assessment Scale (SAS), Self-Depression Scale (SDS), and Pittsburgh Sleep Quality Index (PSQI), levels of serum gamma-interferon (IFN-γ) and interleukin-4 (IL-4) and their ratios, complications, and patient satisfaction with the intervention were observed in both groups. The results showed that the success rate of fetal preservation in the study group (89.36%) was significantly higher than that in the control group (68.09%) (P<0.05). After treatment, SAS, SDS, and PSQI scores decreased in both groups, with the study group being lower (P<0.05). IFN-γ and IFN-γ/IL-4 levels decreased and IL-4 levels increased in both groups after treatment, with IFN-γ and IFN-γ/IL-4 being significantly lower and IL-4 levels being significantly higher in the study group than in the control group (P<0.05). The incidence of adverse drug reactions in the study group was significantly lower than that in the control group (P<0.05). Patients in the study group were more satisfied with all aspects of the intervention than the control group (P<0.05). These results suggest that nurses-physicians collaboration intervention may improve the effectiveness of low-molecular-weight heparin therapy in patients with immune-type RSA. It helps to improve patient pregnancy outcomes, mood, sleep quality, and immune function and increases patient satisfaction.Miaocheng ChenXi WangPeiru DengHindawi LimitedarticleOther systems of medicineRZ201-999ENEvidence-Based Complementary and Alternative Medicine, Vol 2021 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Other systems of medicine RZ201-999
spellingShingle	Other systems of medicine RZ201-999 Miaocheng Chen Xi Wang Peiru Deng Clinical Impact of Nurses-Physicians Collaboration Intervention on the Treatment of Immune Recurrent Spontaneous Abortion with Low-Molecular-Weight Heparin
description	Anticoagulation is currently the preferred and effective treatment for patients with recurrent spontaneous abortion (RSA), but, due to the prevalence of mood disorders in RSA patients and the high number of adverse effects associated with long-term medication, effective care measures are often required. In this study, 94 patients with immune-type RSA who were admitted to our hospital from January 2018 to June 2019 were selected and randomly divided into a control group and a study group of 47 patients each; both groups received low-molecular-weight heparin treatment after admission, and the control group received conventional nursing interventions during treatment, while the patients in the study group received integrated medical and nursing care interventions. Pregnancy outcomes, pre- and postintervention scores on the Self-Assessment Scale (SAS), Self-Depression Scale (SDS), and Pittsburgh Sleep Quality Index (PSQI), levels of serum gamma-interferon (IFN-γ) and interleukin-4 (IL-4) and their ratios, complications, and patient satisfaction with the intervention were observed in both groups. The results showed that the success rate of fetal preservation in the study group (89.36%) was significantly higher than that in the control group (68.09%) (P<0.05). After treatment, SAS, SDS, and PSQI scores decreased in both groups, with the study group being lower (P<0.05). IFN-γ and IFN-γ/IL-4 levels decreased and IL-4 levels increased in both groups after treatment, with IFN-γ and IFN-γ/IL-4 being significantly lower and IL-4 levels being significantly higher in the study group than in the control group (P<0.05). The incidence of adverse drug reactions in the study group was significantly lower than that in the control group (P<0.05). Patients in the study group were more satisfied with all aspects of the intervention than the control group (P<0.05). These results suggest that nurses-physicians collaboration intervention may improve the effectiveness of low-molecular-weight heparin therapy in patients with immune-type RSA. It helps to improve patient pregnancy outcomes, mood, sleep quality, and immune function and increases patient satisfaction.
format	article
author	Miaocheng Chen Xi Wang Peiru Deng
author_facet	Miaocheng Chen Xi Wang Peiru Deng
author_sort	Miaocheng Chen
title	Clinical Impact of Nurses-Physicians Collaboration Intervention on the Treatment of Immune Recurrent Spontaneous Abortion with Low-Molecular-Weight Heparin
title_short	Clinical Impact of Nurses-Physicians Collaboration Intervention on the Treatment of Immune Recurrent Spontaneous Abortion with Low-Molecular-Weight Heparin
title_full	Clinical Impact of Nurses-Physicians Collaboration Intervention on the Treatment of Immune Recurrent Spontaneous Abortion with Low-Molecular-Weight Heparin
title_fullStr	Clinical Impact of Nurses-Physicians Collaboration Intervention on the Treatment of Immune Recurrent Spontaneous Abortion with Low-Molecular-Weight Heparin
title_full_unstemmed	Clinical Impact of Nurses-Physicians Collaboration Intervention on the Treatment of Immune Recurrent Spontaneous Abortion with Low-Molecular-Weight Heparin
title_sort	clinical impact of nurses-physicians collaboration intervention on the treatment of immune recurrent spontaneous abortion with low-molecular-weight heparin
publisher	Hindawi Limited
publishDate	2021
url	https://doaj.org/article/3e5e92657ae3489c8b6ace2f1a720ed4
work_keys_str_mv	AT miaochengchen clinicalimpactofnursesphysicianscollaborationinterventiononthetreatmentofimmunerecurrentspontaneousabortionwithlowmolecularweightheparin AT xiwang clinicalimpactofnursesphysicianscollaborationinterventiononthetreatmentofimmunerecurrentspontaneousabortionwithlowmolecularweightheparin AT peirudeng clinicalimpactofnursesphysicianscollaborationinterventiononthetreatmentofimmunerecurrentspontaneousabortionwithlowmolecularweightheparin
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Clinical Impact of Nurses-Physicians Collaboration Intervention on the Treatment of Immune Recurrent Spontaneous Abortion with Low-Molecular-Weight Heparin

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