Cloudy corneas as an initial presentation of multiple myeloma

Priyanka Sharma,1 Haifa A Madi,1 Richard Bonshek,2 Stephen J Morgan11Sunderland Eye Infirmary, Sunderland, UK; 2National Specialist Ophthalmic Pathology Service, Department of Histopathology, Manchester Royal Infirmary, Manchester, UKSummary: We report a case of previously unsuspected myeloma, pres...

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Autores principales:	Sharma P, Madi HA, Bonshek R, Morgan SJ
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/3e5efb5054344461bb81b76e4ddf29ea
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spelling	oai:doaj.org-article:3e5efb5054344461bb81b76e4ddf29ea2021-12-02T03:05:17ZCloudy corneas as an initial presentation of multiple myeloma1177-5483https://doaj.org/article/3e5efb5054344461bb81b76e4ddf29ea2014-04-01T00:00:00Zhttp://www.dovepress.com/cloudy-corneas-as-an-initial-presentation-of-multiple-myeloma-a16581https://doaj.org/toc/1177-5483 Priyanka Sharma,1 Haifa A Madi,1 Richard Bonshek,2 Stephen J Morgan11Sunderland Eye Infirmary, Sunderland, UK; 2National Specialist Ophthalmic Pathology Service, Department of Histopathology, Manchester Royal Infirmary, Manchester, UKSummary: We report a case of previously unsuspected myeloma, presenting with cornea verticillata due to intracorneal paraprotein deposition.History: An 85-year-old female presented via her optician with a 4-month history of cloudy vision. She had undergone an uneventful bilateral phacoemulsification surgery 7 years earlier. Extensive spiraling corneal epithelial opacification was noted on slit-lamp examination. On further investigation, she was found to have a previously unsuspected low-grade multiple myeloma. We established the nature of the corneal deposits with corneal epithelial biopsy histopathology and electron microscopy. It is very rare for multiple myeloma to present in this fashion. Ophthalmologists should be aware that such a presentation may rarely be due to systemic multiple myeloma.Keywords: corneal crystals, multiple myeloma, crystalline keratopathy, vortex keratopathySharma PMadi HABonshek RMorgan SJDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2014, Iss default, Pp 813-817 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Sharma P Madi HA Bonshek R Morgan SJ Cloudy corneas as an initial presentation of multiple myeloma
description	Priyanka Sharma,1 Haifa A Madi,1 Richard Bonshek,2 Stephen J Morgan11Sunderland Eye Infirmary, Sunderland, UK; 2National Specialist Ophthalmic Pathology Service, Department of Histopathology, Manchester Royal Infirmary, Manchester, UKSummary: We report a case of previously unsuspected myeloma, presenting with cornea verticillata due to intracorneal paraprotein deposition.History: An 85-year-old female presented via her optician with a 4-month history of cloudy vision. She had undergone an uneventful bilateral phacoemulsification surgery 7 years earlier. Extensive spiraling corneal epithelial opacification was noted on slit-lamp examination. On further investigation, she was found to have a previously unsuspected low-grade multiple myeloma. We established the nature of the corneal deposits with corneal epithelial biopsy histopathology and electron microscopy. It is very rare for multiple myeloma to present in this fashion. Ophthalmologists should be aware that such a presentation may rarely be due to systemic multiple myeloma.Keywords: corneal crystals, multiple myeloma, crystalline keratopathy, vortex keratopathy
format	article
author	Sharma P Madi HA Bonshek R Morgan SJ
author_facet	Sharma P Madi HA Bonshek R Morgan SJ
author_sort	Sharma P
title	Cloudy corneas as an initial presentation of multiple myeloma
title_short	Cloudy corneas as an initial presentation of multiple myeloma
title_full	Cloudy corneas as an initial presentation of multiple myeloma
title_fullStr	Cloudy corneas as an initial presentation of multiple myeloma
title_full_unstemmed	Cloudy corneas as an initial presentation of multiple myeloma
title_sort	cloudy corneas as an initial presentation of multiple myeloma
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/3e5efb5054344461bb81b76e4ddf29ea
work_keys_str_mv	AT sharmap cloudycorneasasaninitialpresentationofmultiplemyeloma AT madiha cloudycorneasasaninitialpresentationofmultiplemyeloma AT bonshekr cloudycorneasasaninitialpresentationofmultiplemyeloma AT morgansj cloudycorneasasaninitialpresentationofmultiplemyeloma
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Cloudy corneas as an initial presentation of multiple myeloma

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