Etiologic Characteristics of Enterocolitis in Hospitalized HIV-Infected Patients for 3-Year Period (2013-2015)

Diarrhea is the most common gastrointestinal symptom in HIV-infected patients. The incidence and severity of diarrhea increase with progression of the immune defi ciency. In the literature, 30-60% of the patients with diarrhea among HIV-infected individuals remain without specified etiological agent...

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Autores principales: Yancheva N., Strashimirov D., Elenkov I., Tchervenyakova T., Tomova P., Tcvetkova N., Yankova M., Tomov T., Nikolova M.
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Lenguaje:EN
Publicado: Sciendo 2016
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Acceso en línea:https://doaj.org/article/3e62e8fb10a3480ca9248fe1789ec368
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spelling oai:doaj.org-article:3e62e8fb10a3480ca9248fe1789ec3682021-12-02T19:11:12ZEtiologic Characteristics of Enterocolitis in Hospitalized HIV-Infected Patients for 3-Year Period (2013-2015)0324-175010.1515/amb-2016-0008https://doaj.org/article/3e62e8fb10a3480ca9248fe1789ec3682016-03-01T00:00:00Zhttps://doi.org/10.1515/amb-2016-0008https://doaj.org/toc/0324-1750Diarrhea is the most common gastrointestinal symptom in HIV-infected patients. The incidence and severity of diarrhea increase with progression of the immune defi ciency. In the literature, 30-60% of the patients with diarrhea among HIV-infected individuals remain without specified etiological agent. The aim of this article is to present the incidence of enterocolitis among hospitalized HIV-infected patients over a 3-year period and the degree of etiological clarifi cation of the cause. The results of our analyses showed that 63% of the hospitalized HIV-infected patients for this period were with enterocolitis. Only in 30% of these patients etiological agent was isolated. The reasons for this are mainly financial constraints and, therefore, virological investigations and further endoscopic and histopathological examination of the patients with negative for bacteria and parasites stool samples, were not performed. In the cases with isolated pathogen, an etiological treatment was carried out in parallel with highly active antiretroviral therapy, while in unsubstantiated cases an empirical treatment was carried out. Advanced immune defi ciency was associated with more severe course and worse prognosis of the enterocolitis. The treatment with highly active antiretroviral therapy, which leads to improvement of the immune status of the patients, is essential for the output of enterocolitis in HIV-infected patients.Yancheva N.Strashimirov D.Elenkov I.Tchervenyakova T.Tomova P.Tcvetkova N.Yankova M.Tomov T.Nikolova M.Sciendoarticlehiventerocolitisetiologic diagnosticshighly active antiretroviral therapyMedicineRENActa Medica Bulgarica, Vol 43, Iss 1, Pp 64-70 (2016)
institution DOAJ
collection DOAJ
language EN
topic hiv
enterocolitis
etiologic diagnostics
highly active antiretroviral therapy
Medicine
R
spellingShingle hiv
enterocolitis
etiologic diagnostics
highly active antiretroviral therapy
Medicine
R
Yancheva N.
Strashimirov D.
Elenkov I.
Tchervenyakova T.
Tomova P.
Tcvetkova N.
Yankova M.
Tomov T.
Nikolova M.
Etiologic Characteristics of Enterocolitis in Hospitalized HIV-Infected Patients for 3-Year Period (2013-2015)
description Diarrhea is the most common gastrointestinal symptom in HIV-infected patients. The incidence and severity of diarrhea increase with progression of the immune defi ciency. In the literature, 30-60% of the patients with diarrhea among HIV-infected individuals remain without specified etiological agent. The aim of this article is to present the incidence of enterocolitis among hospitalized HIV-infected patients over a 3-year period and the degree of etiological clarifi cation of the cause. The results of our analyses showed that 63% of the hospitalized HIV-infected patients for this period were with enterocolitis. Only in 30% of these patients etiological agent was isolated. The reasons for this are mainly financial constraints and, therefore, virological investigations and further endoscopic and histopathological examination of the patients with negative for bacteria and parasites stool samples, were not performed. In the cases with isolated pathogen, an etiological treatment was carried out in parallel with highly active antiretroviral therapy, while in unsubstantiated cases an empirical treatment was carried out. Advanced immune defi ciency was associated with more severe course and worse prognosis of the enterocolitis. The treatment with highly active antiretroviral therapy, which leads to improvement of the immune status of the patients, is essential for the output of enterocolitis in HIV-infected patients.
format article
author Yancheva N.
Strashimirov D.
Elenkov I.
Tchervenyakova T.
Tomova P.
Tcvetkova N.
Yankova M.
Tomov T.
Nikolova M.
author_facet Yancheva N.
Strashimirov D.
Elenkov I.
Tchervenyakova T.
Tomova P.
Tcvetkova N.
Yankova M.
Tomov T.
Nikolova M.
author_sort Yancheva N.
title Etiologic Characteristics of Enterocolitis in Hospitalized HIV-Infected Patients for 3-Year Period (2013-2015)
title_short Etiologic Characteristics of Enterocolitis in Hospitalized HIV-Infected Patients for 3-Year Period (2013-2015)
title_full Etiologic Characteristics of Enterocolitis in Hospitalized HIV-Infected Patients for 3-Year Period (2013-2015)
title_fullStr Etiologic Characteristics of Enterocolitis in Hospitalized HIV-Infected Patients for 3-Year Period (2013-2015)
title_full_unstemmed Etiologic Characteristics of Enterocolitis in Hospitalized HIV-Infected Patients for 3-Year Period (2013-2015)
title_sort etiologic characteristics of enterocolitis in hospitalized hiv-infected patients for 3-year period (2013-2015)
publisher Sciendo
publishDate 2016
url https://doaj.org/article/3e62e8fb10a3480ca9248fe1789ec368
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