Structural insights into the mechanism of the membrane integral N-acyltransferase step in bacterial lipoprotein synthesis

Lipoproteins are essential components of bacterial membranes. Here the authors present the crystal structures ofPseudomonas aeruginosa and Escherichia coliapolipoprotein N-acyltransferase, which catalyses the final step in the lipoprotein synthesis pathway, and give insights into its mechanism.

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Autores principales:	Maciej Wiktor, Dietmar Weichert, Nicole Howe, Chia-Ying Huang, Vincent Olieric, Coilín Boland, Jonathan Bailey, Lutz Vogeley, Phillip J. Stansfeld, Nienke Buddelmeijer, Meitian Wang, Martin Caffrey
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3e70da5018ac4c64b19755f2a8e71164
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spelling	oai:doaj.org-article:3e70da5018ac4c64b19755f2a8e711642021-12-02T14:40:24ZStructural insights into the mechanism of the membrane integral N-acyltransferase step in bacterial lipoprotein synthesis10.1038/ncomms159522041-1723https://doaj.org/article/3e70da5018ac4c64b19755f2a8e711642017-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms15952https://doaj.org/toc/2041-1723Lipoproteins are essential components of bacterial membranes. Here the authors present the crystal structures ofPseudomonas aeruginosa and Escherichia coliapolipoprotein N-acyltransferase, which catalyses the final step in the lipoprotein synthesis pathway, and give insights into its mechanism.Maciej WiktorDietmar WeichertNicole HoweChia-Ying HuangVincent OliericCoilín BolandJonathan BaileyLutz VogeleyPhillip J. StansfeldNienke BuddelmeijerMeitian WangMartin CaffreyNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Maciej Wiktor Dietmar Weichert Nicole Howe Chia-Ying Huang Vincent Olieric Coilín Boland Jonathan Bailey Lutz Vogeley Phillip J. Stansfeld Nienke Buddelmeijer Meitian Wang Martin Caffrey Structural insights into the mechanism of the membrane integral N-acyltransferase step in bacterial lipoprotein synthesis
description	Lipoproteins are essential components of bacterial membranes. Here the authors present the crystal structures ofPseudomonas aeruginosa and Escherichia coliapolipoprotein N-acyltransferase, which catalyses the final step in the lipoprotein synthesis pathway, and give insights into its mechanism.
format	article
author	Maciej Wiktor Dietmar Weichert Nicole Howe Chia-Ying Huang Vincent Olieric Coilín Boland Jonathan Bailey Lutz Vogeley Phillip J. Stansfeld Nienke Buddelmeijer Meitian Wang Martin Caffrey
author_facet	Maciej Wiktor Dietmar Weichert Nicole Howe Chia-Ying Huang Vincent Olieric Coilín Boland Jonathan Bailey Lutz Vogeley Phillip J. Stansfeld Nienke Buddelmeijer Meitian Wang Martin Caffrey
author_sort	Maciej Wiktor
title	Structural insights into the mechanism of the membrane integral N-acyltransferase step in bacterial lipoprotein synthesis
title_short	Structural insights into the mechanism of the membrane integral N-acyltransferase step in bacterial lipoprotein synthesis
title_full	Structural insights into the mechanism of the membrane integral N-acyltransferase step in bacterial lipoprotein synthesis
title_fullStr	Structural insights into the mechanism of the membrane integral N-acyltransferase step in bacterial lipoprotein synthesis
title_full_unstemmed	Structural insights into the mechanism of the membrane integral N-acyltransferase step in bacterial lipoprotein synthesis
title_sort	structural insights into the mechanism of the membrane integral n-acyltransferase step in bacterial lipoprotein synthesis
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/3e70da5018ac4c64b19755f2a8e71164
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Structural insights into the mechanism of the membrane integral N-acyltransferase step in bacterial lipoprotein synthesis

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