Transient genome-wide interactions of the master transcription factor NLP7 initiate a rapid nitrogen-response cascade

Conventional methods cannot reveal transient transcription factors (TFs) and targets interactions. Here, Alvarez et al. capture both stable and transient TF-target interactions by time-series ChIP-seq and/or DamID-seq in a cell-based TF perturbation system and show NLP7 as a master TF to initiate a...

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Autores principales: José M. Alvarez, Anna-Lena Schinke, Matthew D. Brooks, Angelo Pasquino, Lauriebeth Leonelli, Kranthi Varala, Alaeddine Safi, Gabriel Krouk, Anne Krapp, Gloria M. Coruzzi
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Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/3e7c1767b2d34c089055f0b932128ac5
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spelling oai:doaj.org-article:3e7c1767b2d34c089055f0b932128ac52021-12-02T17:32:57ZTransient genome-wide interactions of the master transcription factor NLP7 initiate a rapid nitrogen-response cascade10.1038/s41467-020-14979-62041-1723https://doaj.org/article/3e7c1767b2d34c089055f0b932128ac52020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14979-6https://doaj.org/toc/2041-1723Conventional methods cannot reveal transient transcription factors (TFs) and targets interactions. Here, Alvarez et al. capture both stable and transient TF-target interactions by time-series ChIP-seq and/or DamID-seq in a cell-based TF perturbation system and show NLP7 as a master TF to initiate a rapid nitrogen-response cascade.José M. AlvarezAnna-Lena SchinkeMatthew D. BrooksAngelo PasquinoLauriebeth LeonelliKranthi VaralaAlaeddine SafiGabriel KroukAnne KrappGloria M. CoruzziNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
José M. Alvarez
Anna-Lena Schinke
Matthew D. Brooks
Angelo Pasquino
Lauriebeth Leonelli
Kranthi Varala
Alaeddine Safi
Gabriel Krouk
Anne Krapp
Gloria M. Coruzzi
Transient genome-wide interactions of the master transcription factor NLP7 initiate a rapid nitrogen-response cascade
description Conventional methods cannot reveal transient transcription factors (TFs) and targets interactions. Here, Alvarez et al. capture both stable and transient TF-target interactions by time-series ChIP-seq and/or DamID-seq in a cell-based TF perturbation system and show NLP7 as a master TF to initiate a rapid nitrogen-response cascade.
format article
author José M. Alvarez
Anna-Lena Schinke
Matthew D. Brooks
Angelo Pasquino
Lauriebeth Leonelli
Kranthi Varala
Alaeddine Safi
Gabriel Krouk
Anne Krapp
Gloria M. Coruzzi
author_facet José M. Alvarez
Anna-Lena Schinke
Matthew D. Brooks
Angelo Pasquino
Lauriebeth Leonelli
Kranthi Varala
Alaeddine Safi
Gabriel Krouk
Anne Krapp
Gloria M. Coruzzi
author_sort José M. Alvarez
title Transient genome-wide interactions of the master transcription factor NLP7 initiate a rapid nitrogen-response cascade
title_short Transient genome-wide interactions of the master transcription factor NLP7 initiate a rapid nitrogen-response cascade
title_full Transient genome-wide interactions of the master transcription factor NLP7 initiate a rapid nitrogen-response cascade
title_fullStr Transient genome-wide interactions of the master transcription factor NLP7 initiate a rapid nitrogen-response cascade
title_full_unstemmed Transient genome-wide interactions of the master transcription factor NLP7 initiate a rapid nitrogen-response cascade
title_sort transient genome-wide interactions of the master transcription factor nlp7 initiate a rapid nitrogen-response cascade
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/3e7c1767b2d34c089055f0b932128ac5
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