Transient genome-wide interactions of the master transcription factor NLP7 initiate a rapid nitrogen-response cascade
Conventional methods cannot reveal transient transcription factors (TFs) and targets interactions. Here, Alvarez et al. capture both stable and transient TF-target interactions by time-series ChIP-seq and/or DamID-seq in a cell-based TF perturbation system and show NLP7 as a master TF to initiate a...
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2020
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oai:doaj.org-article:3e7c1767b2d34c089055f0b932128ac52021-12-02T17:32:57ZTransient genome-wide interactions of the master transcription factor NLP7 initiate a rapid nitrogen-response cascade10.1038/s41467-020-14979-62041-1723https://doaj.org/article/3e7c1767b2d34c089055f0b932128ac52020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14979-6https://doaj.org/toc/2041-1723Conventional methods cannot reveal transient transcription factors (TFs) and targets interactions. Here, Alvarez et al. capture both stable and transient TF-target interactions by time-series ChIP-seq and/or DamID-seq in a cell-based TF perturbation system and show NLP7 as a master TF to initiate a rapid nitrogen-response cascade.José M. AlvarezAnna-Lena SchinkeMatthew D. BrooksAngelo PasquinoLauriebeth LeonelliKranthi VaralaAlaeddine SafiGabriel KroukAnne KrappGloria M. CoruzziNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020) |
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Science Q José M. Alvarez Anna-Lena Schinke Matthew D. Brooks Angelo Pasquino Lauriebeth Leonelli Kranthi Varala Alaeddine Safi Gabriel Krouk Anne Krapp Gloria M. Coruzzi Transient genome-wide interactions of the master transcription factor NLP7 initiate a rapid nitrogen-response cascade |
description |
Conventional methods cannot reveal transient transcription factors (TFs) and targets interactions. Here, Alvarez et al. capture both stable and transient TF-target interactions by time-series ChIP-seq and/or DamID-seq in a cell-based TF perturbation system and show NLP7 as a master TF to initiate a rapid nitrogen-response cascade. |
format |
article |
author |
José M. Alvarez Anna-Lena Schinke Matthew D. Brooks Angelo Pasquino Lauriebeth Leonelli Kranthi Varala Alaeddine Safi Gabriel Krouk Anne Krapp Gloria M. Coruzzi |
author_facet |
José M. Alvarez Anna-Lena Schinke Matthew D. Brooks Angelo Pasquino Lauriebeth Leonelli Kranthi Varala Alaeddine Safi Gabriel Krouk Anne Krapp Gloria M. Coruzzi |
author_sort |
José M. Alvarez |
title |
Transient genome-wide interactions of the master transcription factor NLP7 initiate a rapid nitrogen-response cascade |
title_short |
Transient genome-wide interactions of the master transcription factor NLP7 initiate a rapid nitrogen-response cascade |
title_full |
Transient genome-wide interactions of the master transcription factor NLP7 initiate a rapid nitrogen-response cascade |
title_fullStr |
Transient genome-wide interactions of the master transcription factor NLP7 initiate a rapid nitrogen-response cascade |
title_full_unstemmed |
Transient genome-wide interactions of the master transcription factor NLP7 initiate a rapid nitrogen-response cascade |
title_sort |
transient genome-wide interactions of the master transcription factor nlp7 initiate a rapid nitrogen-response cascade |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/3e7c1767b2d34c089055f0b932128ac5 |
work_keys_str_mv |
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1718380114362761216 |