Optogenetic control of Bacillus subtilis gene expression
Bacillus subtilis has complex spatial and temporal gene expression patterns but currently lacks optogenetic tools to explore these processes. Here the authors import and debug a cyanobacterial green light sensor pathway and show that it enables precise optical control of gene expression.
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Nature Portfolio
2019
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oai:doaj.org-article:3e7f5ad0191741118843857e0ec930572021-12-02T17:01:53ZOptogenetic control of Bacillus subtilis gene expression10.1038/s41467-019-10906-62041-1723https://doaj.org/article/3e7f5ad0191741118843857e0ec930572019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10906-6https://doaj.org/toc/2041-1723Bacillus subtilis has complex spatial and temporal gene expression patterns but currently lacks optogenetic tools to explore these processes. Here the authors import and debug a cyanobacterial green light sensor pathway and show that it enables precise optical control of gene expression.Sebastian M. Castillo-HairElliot A. BaermanMasaya FujitaOleg A. IgoshinJeffrey J. TaborNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019) |
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Science Q Sebastian M. Castillo-Hair Elliot A. Baerman Masaya Fujita Oleg A. Igoshin Jeffrey J. Tabor Optogenetic control of Bacillus subtilis gene expression |
description |
Bacillus subtilis has complex spatial and temporal gene expression patterns but currently lacks optogenetic tools to explore these processes. Here the authors import and debug a cyanobacterial green light sensor pathway and show that it enables precise optical control of gene expression. |
format |
article |
author |
Sebastian M. Castillo-Hair Elliot A. Baerman Masaya Fujita Oleg A. Igoshin Jeffrey J. Tabor |
author_facet |
Sebastian M. Castillo-Hair Elliot A. Baerman Masaya Fujita Oleg A. Igoshin Jeffrey J. Tabor |
author_sort |
Sebastian M. Castillo-Hair |
title |
Optogenetic control of Bacillus subtilis gene expression |
title_short |
Optogenetic control of Bacillus subtilis gene expression |
title_full |
Optogenetic control of Bacillus subtilis gene expression |
title_fullStr |
Optogenetic control of Bacillus subtilis gene expression |
title_full_unstemmed |
Optogenetic control of Bacillus subtilis gene expression |
title_sort |
optogenetic control of bacillus subtilis gene expression |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/3e7f5ad0191741118843857e0ec93057 |
work_keys_str_mv |
AT sebastianmcastillohair optogeneticcontrolofbacillussubtilisgeneexpression AT elliotabaerman optogeneticcontrolofbacillussubtilisgeneexpression AT masayafujita optogeneticcontrolofbacillussubtilisgeneexpression AT olegaigoshin optogeneticcontrolofbacillussubtilisgeneexpression AT jeffreyjtabor optogeneticcontrolofbacillussubtilisgeneexpression |
_version_ |
1718382022838190080 |