Optogenetic control of Bacillus subtilis gene expression

Bacillus subtilis has complex spatial and temporal gene expression patterns but currently lacks optogenetic tools to explore these processes. Here the authors import and debug a cyanobacterial green light sensor pathway and show that it enables precise optical control of gene expression.

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Autores principales: Sebastian M. Castillo-Hair, Elliot A. Baerman, Masaya Fujita, Oleg A. Igoshin, Jeffrey J. Tabor
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/3e7f5ad0191741118843857e0ec93057
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spelling oai:doaj.org-article:3e7f5ad0191741118843857e0ec930572021-12-02T17:01:53ZOptogenetic control of Bacillus subtilis gene expression10.1038/s41467-019-10906-62041-1723https://doaj.org/article/3e7f5ad0191741118843857e0ec930572019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10906-6https://doaj.org/toc/2041-1723Bacillus subtilis has complex spatial and temporal gene expression patterns but currently lacks optogenetic tools to explore these processes. Here the authors import and debug a cyanobacterial green light sensor pathway and show that it enables precise optical control of gene expression.Sebastian M. Castillo-HairElliot A. BaermanMasaya FujitaOleg A. IgoshinJeffrey J. TaborNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sebastian M. Castillo-Hair
Elliot A. Baerman
Masaya Fujita
Oleg A. Igoshin
Jeffrey J. Tabor
Optogenetic control of Bacillus subtilis gene expression
description Bacillus subtilis has complex spatial and temporal gene expression patterns but currently lacks optogenetic tools to explore these processes. Here the authors import and debug a cyanobacterial green light sensor pathway and show that it enables precise optical control of gene expression.
format article
author Sebastian M. Castillo-Hair
Elliot A. Baerman
Masaya Fujita
Oleg A. Igoshin
Jeffrey J. Tabor
author_facet Sebastian M. Castillo-Hair
Elliot A. Baerman
Masaya Fujita
Oleg A. Igoshin
Jeffrey J. Tabor
author_sort Sebastian M. Castillo-Hair
title Optogenetic control of Bacillus subtilis gene expression
title_short Optogenetic control of Bacillus subtilis gene expression
title_full Optogenetic control of Bacillus subtilis gene expression
title_fullStr Optogenetic control of Bacillus subtilis gene expression
title_full_unstemmed Optogenetic control of Bacillus subtilis gene expression
title_sort optogenetic control of bacillus subtilis gene expression
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/3e7f5ad0191741118843857e0ec93057
work_keys_str_mv AT sebastianmcastillohair optogeneticcontrolofbacillussubtilisgeneexpression
AT elliotabaerman optogeneticcontrolofbacillussubtilisgeneexpression
AT masayafujita optogeneticcontrolofbacillussubtilisgeneexpression
AT olegaigoshin optogeneticcontrolofbacillussubtilisgeneexpression
AT jeffreyjtabor optogeneticcontrolofbacillussubtilisgeneexpression
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