The Second Heart Program-A multidisciplinary team supporting people who inject drugs with infective endocarditis: Protocol of a feasibility study.

<h4>Introduction</h4>Infective endocarditis (IE) is a severe and highly prevalent infection among people who inject drugs (PWID). While short-term (30-day) outcomes are similar between PWID and non-PWID, the long-term outcomes among PWID after IE are poor, with 1-year mortality rates in...

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Autores principales: Robin Lennox, Larkin Lamarche, Leslie Martin, Tim O'Shea, Emilie Belley-Côté, Anna Cvetkovic, Olivia Virag, Richard Whitlock
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Publicado: Public Library of Science (PLoS) 2021
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spelling oai:doaj.org-article:3e96df6e3030480f973a67aee643c79f2021-12-02T20:16:32ZThe Second Heart Program-A multidisciplinary team supporting people who inject drugs with infective endocarditis: Protocol of a feasibility study.1932-620310.1371/journal.pone.0256839https://doaj.org/article/3e96df6e3030480f973a67aee643c79f2021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0256839https://doaj.org/toc/1932-6203<h4>Introduction</h4>Infective endocarditis (IE) is a severe and highly prevalent infection among people who inject drugs (PWID). While short-term (30-day) outcomes are similar between PWID and non-PWID, the long-term outcomes among PWID after IE are poor, with 1-year mortality rates in excess of 25%. Novel clinical interventions are needed to address the unique needs of PWID with IE, including increasing access to substance use treatment and addressing structural barriers and social determinants of health.<h4>Methods and analysis</h4>PWID with IE will be connected to a multidisciplinary team that will transition with them from hospital to the community. The six components of the Second Heart Team are: (1) peer support worker with lived experience, (2) systems navigator, (3) addiction medicine physician, (4) primary care physician, (5) infectious diseases specialist, (6) cardiovascular surgeon. A convergent mixed-methods study design will be used to test the feasibility of this intervention. We will concurrently collect quantitative and qualitative data and 'mix' at the interpretation stage of the study to answer our research questions.<h4>Ethics and dissemination</h4>This study has been approved by the Hamilton Integrated Research Ethics Board (Project No. 7012). Results will be presented at national and international conferences and submitted for publication in a scientific journal.<h4>Clinical trail registrarion</h4>Trial registration number: ISRCTN14968657 https://www.isrctn.com/ISRCTN14968657.Robin LennoxLarkin LamarcheLeslie MartinTim O'SheaEmilie Belley-CôtéAnna CvetkovicOlivia ViragRichard WhitlockPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 10, p e0256839 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Robin Lennox
Larkin Lamarche
Leslie Martin
Tim O'Shea
Emilie Belley-Côté
Anna Cvetkovic
Olivia Virag
Richard Whitlock
The Second Heart Program-A multidisciplinary team supporting people who inject drugs with infective endocarditis: Protocol of a feasibility study.
description <h4>Introduction</h4>Infective endocarditis (IE) is a severe and highly prevalent infection among people who inject drugs (PWID). While short-term (30-day) outcomes are similar between PWID and non-PWID, the long-term outcomes among PWID after IE are poor, with 1-year mortality rates in excess of 25%. Novel clinical interventions are needed to address the unique needs of PWID with IE, including increasing access to substance use treatment and addressing structural barriers and social determinants of health.<h4>Methods and analysis</h4>PWID with IE will be connected to a multidisciplinary team that will transition with them from hospital to the community. The six components of the Second Heart Team are: (1) peer support worker with lived experience, (2) systems navigator, (3) addiction medicine physician, (4) primary care physician, (5) infectious diseases specialist, (6) cardiovascular surgeon. A convergent mixed-methods study design will be used to test the feasibility of this intervention. We will concurrently collect quantitative and qualitative data and 'mix' at the interpretation stage of the study to answer our research questions.<h4>Ethics and dissemination</h4>This study has been approved by the Hamilton Integrated Research Ethics Board (Project No. 7012). Results will be presented at national and international conferences and submitted for publication in a scientific journal.<h4>Clinical trail registrarion</h4>Trial registration number: ISRCTN14968657 https://www.isrctn.com/ISRCTN14968657.
format article
author Robin Lennox
Larkin Lamarche
Leslie Martin
Tim O'Shea
Emilie Belley-Côté
Anna Cvetkovic
Olivia Virag
Richard Whitlock
author_facet Robin Lennox
Larkin Lamarche
Leslie Martin
Tim O'Shea
Emilie Belley-Côté
Anna Cvetkovic
Olivia Virag
Richard Whitlock
author_sort Robin Lennox
title The Second Heart Program-A multidisciplinary team supporting people who inject drugs with infective endocarditis: Protocol of a feasibility study.
title_short The Second Heart Program-A multidisciplinary team supporting people who inject drugs with infective endocarditis: Protocol of a feasibility study.
title_full The Second Heart Program-A multidisciplinary team supporting people who inject drugs with infective endocarditis: Protocol of a feasibility study.
title_fullStr The Second Heart Program-A multidisciplinary team supporting people who inject drugs with infective endocarditis: Protocol of a feasibility study.
title_full_unstemmed The Second Heart Program-A multidisciplinary team supporting people who inject drugs with infective endocarditis: Protocol of a feasibility study.
title_sort second heart program-a multidisciplinary team supporting people who inject drugs with infective endocarditis: protocol of a feasibility study.
publisher Public Library of Science (PLoS)
publishDate 2021
url https://doaj.org/article/3e96df6e3030480f973a67aee643c79f
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